![\"\"](\"http:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/unnamed-file-300x169.png\")
\u00a0“D\u00fcnya n\u00fcfusunun y\u00fczde 12’sinde b\u00f6brek ta\u015f\u0131 g\u00f6r\u00fcl\u00fcyor\u201d<\/p>\n\u00a0“D\u00fcnya n\u00fcfusunun y\u00fczde 12’sinde b\u00f6brek ta\u015f\u0131 g\u00f6r\u00fcl\u00fcyor\u201d<\/p>\n
Dr. \u0130bi\u015f, “100’den fazla damlac\u0131kla 100’den fazla b\u00f6brek ta\u015f\u0131 g\u00f6rd\u00fck”<\/b><\/p>\n
Berfin Baysan – Simge Ar\u0131can – Pelin Ye\u015fil<\/p>\n
Ege \u00dcniversitesi (E\u00dc) M\u00fchendislik Fak\u00fcltesi Biyom\u00fchendislik B\u00f6l\u00fcm\u00fc taraf\u0131ndan “Mikroak\u0131\u015fkan \u00c7ip Teknolojisiyle B\u00f6brek Ta\u015f\u0131 Olu\u015fumu ve \u0130nhibe Edilmesi” semineri \u00e7evrim i\u00e7i olarak ger\u00e7ekle\u015ftirildi. Moderat\u00f6rl\u00fc\u011f\u00fcn\u00fc M\u00fchendislik Fak\u00fcltesi Biyom\u00fchendislik B\u00f6l\u00fcm\u00fc Ba\u015fkan\u0131 Prof. Dr. Bahattin Tanyola\u00e7’\u0131n yapt\u0131\u011f\u0131 semineri Hollanda Delft University Of Tecnology \u00f6\u011fretim \u00fcyesi Dr. Fatma \u0130bi\u015f verdi.<\/p>\n
B\u00f6brek ta\u015f\u0131 olu\u015fumu ve sebeplerinden bahseden Dr. \u0130bi\u015f, “D\u00fcnya n\u00fcfusunun y\u00fczde 12’sinde b\u00f6brek ta\u015f\u0131 g\u00f6r\u00fclmektedir. B\u00f6brek ta\u015f\u0131 \u015fiddetli a\u011fr\u0131n\u0131n yan\u0131 s\u0131ra \u00f6l\u00fcme de sebep olabilmektedir. B\u00f6brek ta\u015f\u0131 iltihab\u0131 nedeniyle her y\u0131l 15 bin ki\u015fi hayat\u0131n\u0131 kaybetmektedir. B\u00f6brek ta\u015f\u0131 olu\u015fumunun sebeplerine bakt\u0131\u011f\u0131m\u0131zda ise genetik, yeme al\u0131\u015fkanl\u0131klar\u0131 ve idrar pH’\u0131ndan kaynakl\u0131 oldu\u011funu s\u00f6ylemek m\u00fcmk\u00fcn. Kalsiyumu, oksalat i\u00e7erikli besinleri \u00e7ok fazla t\u00fcketirsek bir yerden sonra konsantrasyonunu \u00e7ok art\u0131rd\u0131\u011f\u0131m\u0131z i\u00e7in b\u00f6brek ta\u015f\u0131 olu\u015fumuna sebep olabilir. B\u00f6brek ta\u015f\u0131 da kendi i\u00e7inde \u00e7e\u015fitlilik g\u00f6stermektedir. Bunlar; kalsiyum oksalat ta\u015flar\u0131, \u00fcrik asit ta\u015f\u0131, strutive (enfeksiyon ta\u015f\u0131) ve sistin ta\u015f\u0131 olarak kategorilere ay\u0131rabiliriz. En s\u0131k g\u00f6r\u00fclen b\u00f6brek ta\u015f\u0131 \u00e7e\u015fidi ise kalsiyum oksalat monohidrat (COM)’dur. B\u00f6brek ta\u015f\u0131 olu\u015fumu \u00f6ncelikle berrak \u00e7\u00f6zeltide ba\u015flar ve uygun ortamda, minerallerin bir araya gelmesi ile \u00e7ekirdeklenir ve ard\u0131ndan \u00e7ekirdeklerin birle\u015fmesiyle kristal olu\u015fur. Kristaller bir araya gelerek b\u00f6brek ta\u015f\u0131n\u0131 olu\u015fturur” dedi.<\/p>\n
\u201cDeney s\u00fcresini k\u0131saltarak 500 saatten 5 saate d\u00fc\u015f\u00fcrd\u00fck\u201d<\/b><\/p>\n
Yapt\u0131\u011f\u0131 deneylerden ve s\u00fcrecinden bahseden Dr. \u0130bi\u015f, “Yapt\u0131\u011f\u0131m\u0131z deneyde mikroak\u0131\u015fkan teknolojiyle COM \u00e7ekirdeklenmesinin kineti\u011finin anla\u015f\u0131lmas\u0131n\u0131 ama\u00e7lad\u0131k. Bunu anlamak \u00e7ok \u00f6nemli \u00e7\u00fcnk\u00fc b\u00f6brek ta\u015f\u0131n\u0131 \u00f6nleyebilmemiz i\u00e7in hangi reaksiyonun hangi ko\u015fullarda ne zaman oldu\u011funu bilmemiz gerekiyor. Bu kapsamda 5 tane konsantrasyonda doygunlu\u011fa (S), 3 tane pH de\u011ferine\u00a0 bakt\u0131k. 5 tane magnezyum de\u011ferini (Mg) ve 3 tane de farkl\u0131 OPN ekledik. Ama biz bu deneyi k\u00fc\u00e7\u00fck bir kap veya beherde yapmad\u0131k. \u00c7\u00fcnk\u00fc art\u0131k teknoloji buna elveri\u015fliydi ve mikroak\u0131\u015fkan \u00e7ip kullanmak bizim i\u00e7in zaman, emek,\u00a0 malzeme ve para kayb\u0131n\u0131 azalt\u0131yordu. Kendi dizayn etti\u011fimiz mikroak\u0131\u015fkan \u00e7ipimizi kulland\u0131k. Burada mikrolitre biriminde k\u00fc\u00e7\u00fck damlac\u0131klar olu\u015fturduk ve ayn\u0131 anda ayn\u0131 \u00f6zellikte \u00e7ok say\u0131da deney yapabildik. Her bir damlac\u0131k kendi ba\u015f\u0131na ayr\u0131 bir mikroreakt\u00f6rd\u00fc. Bu damlac\u0131klar \u00e7emberlere yerle\u015fiyor ve dakikalar i\u00e7erisinde anl\u0131k b\u00f6brek ta\u015f\u0131 olu\u015fumunu tespit ediyoruz. Peki, bu mikro\u00e7ip bize ne sa\u011flad\u0131? Damla i\u00e7inde b\u00f6brek ta\u015f\u0131 tespit etmemizi sa\u011flad\u0131 ve 100’den fazla damlac\u0131kla 100’den fazla b\u00f6brek ta\u015f\u0131 g\u00f6rd\u00fck. Deney s\u00fcresini k\u0131saltarak 500 saatten 5 saate d\u00fc\u015f\u00fcrd\u00fck. Malzeme kullan\u0131m\u0131nda y\u00fczde 1’e d\u00fc\u015f\u00fcrd\u00fck ve maliyet a\u00e7\u0131s\u0131ndan kazan\u00e7 sa\u011flad\u0131k” dedi.<\/p>\n
\u201cB\u00f6brekler hala bilim d\u00fcnyas\u0131 i\u00e7in b\u00fcy\u00fck bir kara kutu\u201d<\/b><\/p>\n
Sa\u011fl\u0131kl\u0131 bir insandaki, idrar pH de\u011ferinin b\u00f6brek ta\u015f\u0131 olu\u015fumunda engelleyici bir fakt\u00f6r oldu\u011funu ifade eden Dr. \u0130bi\u015f, “\u0130drar pH’\u0131m\u0131z 6’dan d\u00fc\u015f\u00fck veya y\u00fcksekse b\u00f6brek ta\u015f\u0131 olu\u015fumuna uygun bir ortam elde edilir. Yapt\u0131\u011f\u0131m\u0131z deney de literat\u00fcrde olmayan bir \u00e7al\u0131\u015fmayd\u0131 ve g\u00f6zlemlediklerimiz aras\u0131nda idrar pH 6’da b\u00f6brek ta\u015f\u0131 olu\u015fumuna rastlamad\u0131k. Asl\u0131nda b\u00f6brekler hala bilim d\u00fcnyas\u0131 i\u00e7in b\u00fcy\u00fck bir kara kutu. Bu \u00e7e\u015fit deneylerin yap\u0131l\u0131p b\u00f6brek ta\u015f\u0131n\u0131n e\u015f zamanl\u0131 olarak k\u00fc\u00e7\u00fck \u00e7apta g\u00f6zlenebilmesi b\u00fcy\u00fck bir ad\u0131md\u0131 bunu g\u00f6rm\u00fc\u015f olduk. B\u00f6brek ta\u015f\u0131 olu\u015fumunda bir s\u00fcr\u00fc fakt\u00f6r var ama bir yerden sonra bu fakt\u00f6rlerin asl\u0131nda ki\u015fiye ba\u011fl\u0131 de\u011fi\u015fti\u011fi de s\u00f6ylenebilir. Ki\u015fiye ba\u011fl\u0131 tedavi y\u00f6ntemleri de anlaml\u0131 olabilir. Bu tedavi y\u00f6ntemlerinin ki\u015fiye ba\u011fl\u0131 olabilmesi ve bunun yap\u0131labilmesi i\u00e7in mikro\u00e7ip \u015feklindeki cihazlara ihtiya\u00e7 var” dedi.<\/p>\n
<\/a>\n\t\t\t<\/div><\/figure><\/a>\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n\n","protected":false},"excerpt":{"rendered":"\u00a0“D\u00fcnya n\u00fcfusunun y\u00fczde 12’sinde b\u00f6brek ta\u015f\u0131 g\u00f6r\u00fcl\u00fcyor\u201d Dr. \u0130bi\u015f, “100’den fazla damlac\u0131kla 100’den fazla b\u00f6brek…<\/p>\n","protected":false},"author":2,"featured_media":5929,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,1,70,68],"tags":[],"class_list":["post-5928","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim","category-gncl","category-kampus","category-saglik"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis.png",1600,900,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-150x150.png",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-300x169.png",300,169,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-768x432.png",640,360,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-1024x576.png",640,360,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-1536x864.png",1536,864,true],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis.png",1600,900,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-1280x720.png",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-1024x576.png",1024,576,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/12\/dr.fatma-ibis-720x380.png",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> G\u00fcncel<\/a> Kamp\u00fcs<\/a> Sa\u011fl\u0131k<\/a>","tag_info":"Sa\u011fl\u0131k","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/5928","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=5928"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/5928\/revisions"}],"predecessor-version":[{"id":5933,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/5928\/revisions\/5933"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/5929"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=5928"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=5928"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=5928"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}