Ege \u00dcniversitesi (E\u00dc) Fen Fak\u00fcltesi Dekan\u0131 ve \u00a0\u00a0Biyoloji B\u00f6l\u00fcm\u00fc Temel ve End\u00fcstriyel Mikrobiyoloji Ana Bilim Dal\u0131 \u00f6\u011fretim \u00fcyesi Prof. Dr. \u0130hsan Ya\u015fa\u2019n\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131, \u201cPhotobacterium Damselae Subsp. Piscicida Virulans Fakt\u00f6r\u00fc Sideroforunun (Piscibactin) \u0130zolasyonu, Yap\u0131 Tayini ve Siderofor Molek\u00fcl\u00fcne Y\u00f6nelik Aptamer Bazl\u0131 Antimikrobiyal (Aptabiyotik) Geli\u015ftirilmesi\u201d ba\u015fl\u0131kl\u0131 projesi, T\u00dcB\u0130TAK “1001-Bilimsel ve Teknolojik Ara\u015ft\u0131rma Projelerini Destekleme Program\u0131” kapsam\u0131nda desteklenmeye hak kazand\u0131.<\/p>\n
Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, Prof. Dr. \u0130hsan Ya\u015fa\u2019y\u0131 ve proje ara\u015ft\u0131rmac\u0131lar\u0131 Fen Fak\u00fcltesi Biyokimya Ana Bilim Dal\u0131 \u00f6\u011fretim \u00fcyesi Do\u00e7. Dr. Serap Evran, Fen Fak\u00fcltesi Kimya B\u00f6l\u00fcm\u00fc Organik Kimya Ana Bilim Dal\u0131 \u00f6\u011fretim \u00fcyesi Do\u00e7. Dr. Nazl\u0131 Sar\u0131kahya ve Fen Fak\u00fcltesi Biyoloji B\u00f6l\u00fcm\u00fc Temel ve End\u00fcstriyel Mikrobiyoloji Ana Bilim Dal\u0131 ara\u015ft\u0131rma g\u00f6revlisi Asiye Esra Eren\u2019i tebrik ederek, ba\u015far\u0131lar diledi. Rekt\u00f6r Budak, \u201c\u00dcniversitemiz, T\u00dcB\u0130TAK 2021 y\u0131l\u0131 1. d\u00f6neminde \u2018Bilimsel ve Teknolojik Ara\u015ft\u0131rma Projelerini Destekleme Program\u0131\u2019 kapsam\u0131nda, sonraki d\u00f6nemi beklemeden tekrar ba\u015fvurulabilen projelerin de\u011ferlendirmesinde en \u00e7ok kabul alan y\u00fcksek\u00f6\u011fretim kurumu oldu. Program kapsam\u0131nda Ege \u00dcniversitesi \u00f6\u011fretim elemanlar\u0131 taraf\u0131ndan y\u00fcr\u00fct\u00fclen 25 proje destek almaya hak kazand\u0131. De\u011ferli akademisyenlerimizin y\u00fcr\u00fctt\u00fckleri bu proje, antibiyotik direncine kar\u015f\u0131 s\u00fcrd\u00fcr\u00fclebilir stratejilerin geli\u015ftirilmesine y\u00f6nelik y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmalara katk\u0131 sunmay\u0131 hedefliyor.\u00a0 T\u00dcB\u0130TAK taraf\u0131ndan desteklenmeye hak kazanan bu proje ve daha nice ba\u015far\u0131l\u0131 proje, bilime ve insanl\u0131k yarar\u0131na katk\u0131 sunmaya devam edecek. Akademisyenlerimizi tebrik ediyor, \u00e7al\u0131\u015fmalar\u0131nda ba\u015far\u0131lar\u0131n\u0131n devam\u0131n\u0131 diliyorum\u201d dedi.<\/p>\n
Projenin konusu, D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc\u2019n\u00fcn acil eylem planlar\u0131 aras\u0131nda<\/b><\/p>\n
Proje hakk\u0131nda bilgi veren Prof. Dr. Ya\u015fa, \u201c\u00dclkemizde su \u00fcr\u00fcnleri yeti\u015ftiricili\u011fi h\u0131zla geli\u015fen bir end\u00fcstridir ve ticari a\u00e7\u0131dan \u00f6nemli bir gelir kayna\u011f\u0131 olmakla birlikte hayvansal protein kayna\u011f\u0131 olarak da gelecekte olas\u0131 a\u00e7\u0131\u011f\u0131n kapat\u0131lmas\u0131nda stratejik \u00f6neme sahiptir. Di\u011fer bir taraftan, su \u00fcr\u00fcnleri yeti\u015ftiricili\u011finin h\u0131zl\u0131 bir \u015fekilde b\u00fcy\u00fcmesi, bal\u0131k kalitesi ve g\u00fcvenli\u011fi ile ilgili \u00e7e\u015fitli endi\u015felere neden oluyor. Bakteriyal enfeksiyon hastal\u0131klar\u0131 k\u00fclt\u00fcr bal\u0131k\u00e7\u0131l\u0131\u011f\u0131n\u0131n en b\u00fcy\u00fck tehlikelerinden biri ve salg\u0131nlar ba\u015flad\u0131\u011f\u0131nda \u00f6nemli \u00f6l\u00e7\u00fcde \u00fcr\u00fcn kay\u0131plar\u0131 ya\u015fan\u0131yor. Diren\u00e7li bakterilerin antibiyotik diren\u00e7 genlerinin su ortam\u0131ndaki di\u011fer bakterilere ve insan patojenlerine transferi, insan sa\u011fl\u0131\u011f\u0131 i\u00e7in de ciddi bir risk olu\u015fturuyor. Global halk sa\u011fl\u0131\u011f\u0131 a\u00e7\u0131s\u0131ndan bak\u0131ld\u0131\u011f\u0131nda antimikrobiyal dirence ba\u011fl\u0131 olarak her y\u0131l yakla\u015f\u0131k 700 bin ki\u015finin hayat\u0131n\u0131 kaybetti\u011fi bilinmekte ve \u00f6nlem al\u0131namaz ise 2050 y\u0131l\u0131na kadar bu say\u0131n\u0131n 10 milyon ki\u015fiye ula\u015faca\u011f\u0131 \u00f6ng\u00f6r\u00fcl\u00fcyor. D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc\u2019n\u00fcn de acil eylem planlar\u0131 aras\u0131nda yer alan antibiyotik direncine kar\u015f\u0131 s\u00fcrd\u00fcr\u00fclebilir stratejilerin geli\u015ftirilmesine y\u00f6nelik faj terapi \u00e7al\u0131\u015fmalar\u0131m\u0131za ilave yeni bir yakla\u015f\u0131m\u0131 da bu proje ile uygulamaya ge\u00e7iriyoruz\u201d diye konu\u015ftu.<\/p>\n
\u201cDo\u011fay\u0131 koruyan d\u00f6ng\u00fcsel bir model hedefleniyor\u201d<\/b><\/p>\n
Projenin antimikrobiyal diren\u00e7le m\u00fccadelede yeni s\u00fcrd\u00fcr\u00fclebilir bir strateji hedefledi\u011fini belirten Prof. Dr. Ya\u015fa, \u201cProjemiz antimikrobiyal diren\u00e7le m\u00fccadeleye y\u00f6nelik yeni ve s\u00fcrd\u00fcr\u00fclebilir bir yakla\u015f\u0131m niteli\u011finde. Proje sonucunda bakteriye \u00f6zg\u00fc bir virulans fakt\u00f6r\u00fc olan siderofor molek\u00fcl\u00fc ile spesifik etkile\u015fime girecek ve yap\u0131sal veya fonksiyonel hasara yol a\u00e7acak oligon\u00fckleotid molek\u00fclleri \u00a0sadece su \u00fcr\u00fcnleri yeti\u015ftiricili\u011fi alan\u0131nda de\u011fil, patojen mikroorganizmalarla m\u00fccadele edilen her alana uyarlanabilecektir. Aptamer bazl\u0131 tasarlad\u0131\u011f\u0131m\u0131z bu yeni yakla\u015f\u0131m sayesinde yaln\u0131zca salg\u0131n kayna\u011f\u0131 patojen bakteriler hedeflenebilecek, dolay\u0131s\u0131yla Ye\u015fil Mutabakat kapsam\u0131nda biyo\u00e7e\u015fitlili\u011fi, do\u011fay\u0131 koruyan d\u00f6ng\u00fcsel bir model olu\u015fturacakt\u0131r\u201d diye konu\u015ftu.<\/p>\n","protected":false},"excerpt":{"rendered":"
Ege \u00dcniversitesi (E\u00dc) Fen Fak\u00fcltesi Dekan\u0131 ve \u00a0\u00a0Biyoloji B\u00f6l\u00fcm\u00fc Temel ve End\u00fcstriyel Mikrobiyoloji Ana Bilim…<\/p>\n","protected":false},"author":2,"featured_media":4798,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4797","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gncl"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA.jpg",1500,1000,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA-768x512.jpg",640,427,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA-1024x683.jpg",640,427,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA.jpg",1500,1000,false],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA.jpg",1500,1000,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA-1024x683.jpg",1024,683,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Prof.-Dr.-Ihsan-YASA-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"G\u00fcncel<\/a>","tag_info":"G\u00fcncel","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/4797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=4797"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/4797\/revisions"}],"predecessor-version":[{"id":4799,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/4797\/revisions\/4799"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/4798"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=4797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=4797"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=4797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}