{"id":4621,"date":"2021-09-01T12:31:14","date_gmt":"2021-09-01T12:31:14","guid":{"rendered":"https:\/\/www.euegeajans.com\/?p=4621"},"modified":"2021-09-01T12:31:15","modified_gmt":"2021-09-01T12:31:15","slug":"turkiyede-ilk-kez-uygulanan-yontemle-8-hasta-sagligina-kavustu","status":"publish","type":"post","link":"https:\/\/www.euegeajans.com\/index.php\/2021\/09\/01\/turkiyede-ilk-kez-uygulanan-yontemle-8-hasta-sagligina-kavustu\/","title":{"rendered":"T\u00fcrkiye\u2019de ilk kez uygulanan y\u00f6ntemle 8 hasta sa\u011fl\u0131\u011f\u0131na kavu\u015ftu"},"content":{"rendered":"

\u00a0Hemofili gen tedavisine Ege\u2019den bir ilk daha<\/p>\n

Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi (E\u00dcTF) \u00c7ocuk Sa\u011fl\u0131\u011f\u0131 ve Hastal\u0131klar\u0131 Hastanesinde, Hemofili-A hastalar\u0131na y\u00f6nelik Faz-3 ara\u015ft\u0131rmas\u0131 kapsam\u0131nda T\u00fcrkiye\u2019de ilk kez 8 hastaya gen tedavisi uyguland\u0131. E\u00dc Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, uluslararas\u0131 ara\u015ft\u0131rmada yer alarak T\u00fcrkiye\u2019de bir ilke imza atan E\u00dcTF \u00c7ocuk Sa\u011fl\u0131\u011f\u0131 ve Hastal\u0131klar\u0131 Anabilim Dal\u0131 Ba\u015fkan\u0131 Prof. Dr. Kaan Kavakl\u0131 ve ekibini tebrik etti. Prof. Dr. Kavakl\u0131, daha \u00f6nce Hemofili-B hastalar\u0131na yine T\u00fcrkiye\u2019de ilk kez gen tedavisi uygulad\u0131klar\u0131n\u0131, bu ara\u015ft\u0131rmada da ilk olman\u0131n mutlulu\u011funu ya\u015fad\u0131klar\u0131n\u0131 s\u00f6yledi.<\/p>\n

\"\"E\u00dcTF \u00c7ocuk Sa\u011fl\u0131\u011f\u0131 ve Hastal\u0131klar\u0131 Hastanesi, hemofili hastalar\u0131na umut olmaya devam ediyor. Ge\u00e7en y\u0131l, 4 Hemofili-B hastas\u0131na T\u00fcrkiye\u2019de ilk kez gen tedavisi uygulayan E\u00dcTF \u00c7ocuk Sa\u011fl\u0131\u011f\u0131 ve Hastal\u0131klar\u0131 Anabilim Dal\u0131 Ba\u015fkan\u0131 Prof. Dr. Kaan Kavakl\u0131 ve ekibi, uluslararas\u0131 yeni projede bu kez Hemofili-A tan\u0131l\u0131 ya\u015flar\u0131 18-25 aras\u0131ndaki 8 hastaya gen tedavisi uygulad\u0131. Hemofili Federasyonu Genel Ba\u015fkan\u0131 da olan Prof. Dr. Kavakl\u0131 ekibiyle E\u00dc Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak\u2019\u0131 ziyaret edip \u00e7al\u0131\u015fmalar\u0131 hakk\u0131nda bilgi verdi.<\/p>\n

EGE\u2019N\u0130N ADI B\u0130L\u0130MLE ANILIYOR<\/b><\/p>\n

Ege \u00dcniversitesindeki bilim ikliminin her alanda kendisini g\u00f6sterdi\u011fini dile getiren Rekt\u00f6r Budak, \u201cY\u00fcksek\u00f6\u011fretim Kalite Kurulu taraf\u0131ndan uygulanan Kurumsal Akreditasyon Program\u0131 kapsam\u0131nda 5 y\u0131l s\u00fcreyle \u2018Tam akreditasyon\u2019 alan \u00fcniversitemizin ad\u0131 bilimle an\u0131l\u0131yor. Her alanda donan\u0131ml\u0131 akademik kadromuz \u00f6nemli ba\u015far\u0131lara imza at\u0131yor. Kaan hocam\u0131z ve ekibi ge\u00e7en y\u0131l da bir ilke imza atm\u0131\u015ft\u0131, bu y\u0131l i\u00e7inde yer ald\u0131klar\u0131 uluslararas\u0131 projeyi bir ad\u0131m daha ileriye ta\u015f\u0131d\u0131. Ge\u00e7en y\u0131l 4 hastaya uygulanan gen tedavisi bu y\u0131l 8 hastaya uyguland\u0131 ve hastalar\u0131m\u0131z sa\u011fl\u0131\u011f\u0131na kavu\u015ftu. Hocam\u0131z\u0131 ve ekip arkada\u015flar\u0131n\u0131 tebrik ediyorum\u201d dedi.<\/p>\n

HAYAT BOYU S\u00dcREB\u0130LECEK \u0130Y\u0130LE\u015eME S\u00dcREC\u0130<\/b><\/p>\n

Hemofili hastal\u0131\u011f\u0131n\u0131n 10 binde 1 g\u00f6r\u00fcld\u00fc\u011f\u00fcne dikkat \u00e7eken Prof. Dr. Kavakl\u0131, \u201cHemofili hayat boyu s\u00fcren ciddi bir\"\" genetik kan hastal\u0131\u011f\u0131d\u0131r. V\u00fccuttaki p\u0131ht\u0131la\u015fma fakt\u00f6rleri yeterince g\u00f6revini yapam\u0131yor. Sonu\u00e7ta p\u0131ht\u0131 olu\u015fumu yetersiz oldu\u011fu hastalar kanamalar nedeniyle hayati riske giriyor. Kanamalar\u0131n durmas\u0131 i\u00e7in hasta ya\u015fam\u0131 boyunca ila\u00e7 kullanmak zorunda kal\u0131yor. Hastal\u0131\u011f\u0131n te\u015fhisi bebeklik d\u00f6neminde konuyor. Sonraki s\u00fcre\u00e7te hasta takip ediliyor. Gen tedavisinde ama\u00e7lad\u0131\u011f\u0131m\u0131z \u015fey, hastan\u0131n, hayat boyu s\u00fcrecek tamamen iyile\u015fmesi\u201d diye konu\u015ftu.<\/p>\n

HEMOF\u0130L\u0130 HASTALARINA UMUT OLACAK<\/b><\/p>\n

Amerika Birle\u015fik Devletleri (ABD) ile ortakla\u015fa y\u00fcr\u00fctt\u00fckleri proje kapsam\u0131nda, ara\u015ft\u0131rma a\u015famas\u0131ndaki ilac\u0131n eksi 80 derece T\u00fcrkiye\u2019ye getirildi\u011fini ve uygun hastalarda, uygun zaman ve dozda deneyimli bir kadro taraf\u0131ndan uyguland\u0131\u011f\u0131na dikkat \u00e7eken Prof. Dr. Kavakl\u0131, uygulanan y\u00f6nteme y\u00f6nelik uluslararas\u0131 ara\u015ft\u0131rmalar\u0131n s\u00fcrd\u00fc\u011f\u00fcn\u00fc ve 1 y\u0131ll\u0131k bir s\u00fcre\u00e7 i\u00e7inde ABD G\u0131da ve \u0130la\u00e7 Dairesi (FDA) taraf\u0131ndan onaylanmas\u0131n\u0131 beklediklerini vurgulad\u0131. Gen tedavisinin hemofili hastalar\u0131n\u0131n sa\u011fl\u0131\u011f\u0131na kavu\u015fmas\u0131 anlam\u0131nda umut olaca\u011f\u0131n\u0131 kaydeden Prof. Dr. Kavakl\u0131, \u201cEge \u00dcniversitesi kanama p\u0131ht\u0131la\u015fma hastal\u0131klar\u0131nda olduk\u00e7a deneyimli bir \u00fcniversite. 30 y\u0131l\u0131k bir merkezimiz var zaten. Biz merkezi biraz daha iyi hale getirdik. Bu alanda da 20 y\u0131ld\u0131r \u00e7al\u0131\u015fmalar yap\u0131yoruz. Uluslararas\u0131 bilimsel \u00e7al\u0131\u015fmalara imza at\u0131yoruz. Deneyimli hocalar\u0131m\u0131z var. G\u00fc\u00e7l\u00fc bir ekibimiz var, Ege \u00dcniversitesinin projede yer almas\u0131n\u0131n nedeni bu. Ege \u00dcniversitesinin bu ba\u015far\u0131s\u0131 uluslararas\u0131 klinik Faz-3 ila\u00e7 ara\u015ft\u0131rmas\u0131 format\u0131nda, Amerika, \u0130ngiltere, Fransa ve Almanya\u2019daki merkezlerle ortak olarak \u00e7al\u0131\u015f\u0131l\u0131yor. Hayat boyu s\u00fcren ve haftada 2-3 kez damar yoluyla fakt\u00f6r ilac\u0131 almak zorunda olan hemofili hastalar\u0131 gen tedavisi uygulamas\u0131 ile hayat boyu s\u00fcrebilecek iyile\u015fme s\u00fcreci ya\u015f\u0131yor. Herhangi bir ameliyat ya da diki\u015f s\u00f6z konusu de\u011fil. Gen tedavisi uzman personel taraf\u0131ndan haz\u0131rlanan serumun 4 saatlik bir s\u00fcrede hastaya verilmesiyle tamamlan\u0131yor. Gen tedavisi uygulanan 8 hastam\u0131z\u0131 takip ediyoruz, aralar\u0131nda bankac\u0131, \u00f6\u011fretmeni \u00f6\u011frenci olanlar var hastal\u0131klar\u0131na ili\u015fkin ila\u00e7 kullanmalar\u0131na gerek kalmadan normal ya\u015famlar\u0131na devam ediyorlar\u201d diye konu\u015ftu.<\/p>\n

\u201cT\u00dcRK\u0130YE\u2019DE 6-7 B\u0130N HASTA VAR\u201d<\/b><\/p>\n

Proje kapsam\u0131nda hastalara 1 kez gen tedavisinin uyguland\u0131\u011f\u0131n\u0131 dile getiren Prof. Dr. Kavakl\u0131, \u201cGenetik nadir bir hastal\u0131k diyoruz ama T\u00fcrkiye\u2019de 6-7 bin hasta var. Bunlardan en az 4-5 bini a\u011f\u0131r hasta ve gen tedavisine aday hastalar. Bu hastalar, Sosyal G\u00fcvenlik Kurumunun geri \u00f6demesini yapt\u0131\u011f\u0131, Avrupa ve Amerika\u2019dan gelen biyolojik \u00fcr\u00fcnlerle ge\u00e7ici olarak kanamalar\u0131 durduruluyor. Ama kal\u0131c\u0131 bir iyile\u015fme sa\u011flamak sadece gen tedavisiyle m\u00fcmk\u00fcn dedi.<\/p>\n

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\u00a0Hemofili gen tedavisine Ege\u2019den bir ilk daha Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi (E\u00dcTF) \u00c7ocuk Sa\u011fl\u0131\u011f\u0131 ve…<\/p>\n","protected":false},"author":2,"featured_media":4624,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4621","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gncl"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4.jpeg",1024,683,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4-150x150.jpeg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4-300x200.jpeg",300,200,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4-768x512.jpeg",640,427,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4.jpeg",640,427,false],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4.jpeg",1024,683,false],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4.jpeg",1024,683,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4.jpeg",1024,683,false],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4.jpeg",1024,683,false],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/09\/Hemofili-gen-tedavisine-Ege4-720x380.jpeg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"G\u00fcncel<\/a>","tag_info":"G\u00fcncel","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/4621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=4621"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/4621\/revisions"}],"predecessor-version":[{"id":4625,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/4621\/revisions\/4625"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/4624"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=4621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=4621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=4621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}