{"id":3117,"date":"2021-04-08T04:48:00","date_gmt":"2021-04-08T04:48:00","guid":{"rendered":"http:\/\/www.euegeajans.com\/?p=3117"},"modified":"2021-04-08T06:58:50","modified_gmt":"2021-04-08T06:58:50","slug":"antikor-testi-yalanci-bir-guven-hissi-verebilir","status":"publish","type":"post","link":"https:\/\/www.euegeajans.com\/index.php\/2021\/04\/08\/antikor-testi-yalanci-bir-guven-hissi-verebilir\/","title":{"rendered":"\u201cAntikor testi yalanc\u0131 bir g\u00fcven hissi verebilir\u201d"},"content":{"rendered":"

\"\"Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi (E\u00dcTF) T\u0131bbi Mikrobiyoloji Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi ve T\u0131bbi Viroloji Bilim Dal\u0131 Ba\u015fkan\u0131 Prof. Dr. Selda Erensoy, gereksiz yere, doktor talebi olmaks\u0131z\u0131n ve uzmanlar\u0131 taraf\u0131ndan de\u011ferlendirilmeyen antikor testlerinin ki\u015filerde kafa kar\u0131\u015f\u0131kl\u0131\u011f\u0131 ve yanl\u0131\u015f bir g\u00fcven hissi olu\u015fturabilece\u011fine dikkat \u00e7ekti. A\u015f\u0131lananlar\u0131n say\u0131s\u0131n\u0131n artmas\u0131yla antikor testlerine de talebin artt\u0131\u011f\u0131na vurgu yapan Prof. Dr. Erensoy, antikor testi i\u00e7in kullan\u0131lan kitlerin hen\u00fcz standardizasyonunun tamamlanmad\u0131\u011f\u0131n\u0131 ve bu testlerin sonu\u00e7lar\u0131na g\u00fcvenerek hareket edilmemesi gerekti\u011fini s\u00f6yledi.<\/p>\n

Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi (E\u00dcTF) T\u0131bbi Mikrobiyoloji Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi ve T\u0131bbi Viroloji Bilim Dal\u0131 Ba\u015fkan\u0131 Prof. Dr. Selda Erensoy, Covid-19 pandemisinin a\u011f\u0131rla\u015ft\u0131\u011f\u0131 bug\u00fcnlerde, mikrobiyolojik tan\u0131 testlerinin do\u011fru kullan\u0131lmas\u0131, do\u011fru \u015fekilde yorumlanmas\u0131 ve testlerin do\u011fru \u015fekilde se\u00e7ilmesinin salg\u0131n kontrol\u00fcnde kritik \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131n\u0131n alt\u0131n\u0131 \u00e7izdi. Klinik Mikrobiyoloji Uzmanl\u0131k Derne\u011fi Y\u00f6netim Kurulu Ba\u015fkan\u0131 da olan Prof. Dr. Erensoy, Covid-19 antikor testlerinin kontrols\u00fcz ve uygun olmayan \u015fekillerde yayg\u0131n olarak kullan\u0131lmaya ve yorumlanmaya ba\u015flad\u0131\u011f\u0131n\u0131 s\u00f6yledi.<\/p>\n

\u201cANT\u0130KOR TEST\u0130 UYGUN OLMAYAN B\u0130R \u015eEK\u0130LDE \u0130LG\u0130 ODA\u011eI HAL\u0130NE GELD\u0130\u201d<\/strong><\/p>\n

Belirtili ya da belirtisiz Covid-19 hastal\u0131\u011f\u0131n\u0131 ge\u00e7iren bir ki\u015finin v\u00fccudunun vir\u00fcse kar\u015f\u0131 spesifik antikor geli\u015ftirdi\u011fini hat\u0131rlatan Prof. Dr. Erensoy, \u201cAyn\u0131 zamanda a\u015f\u0131 etkinli\u011finin merak edildi\u011fi bu d\u00f6nemde, a\u015f\u0131 yapt\u0131rd\u0131ktan sonra antikorlara bakt\u0131r\u0131lmas\u0131 da ilgi oda\u011f\u0131 oldu. Ancak Covid-19 a\u015f\u0131s\u0131ndan sonra bireysel karar vermek ve de yorum yapmak i\u00e7in antikor testlerinin yap\u0131lmas\u0131 \u00f6nerilmemektedir\u201d diye konu\u015ftu.<\/p>\n

\u201cYALANCI G\u00dcVEN H\u0130SS\u0130 VEREB\u0130L\u0130R\u201d<\/strong><\/p>\n

\"\"Bireysel olarak yapt\u0131r\u0131lan antikor testlerinin hem kafa kar\u0131\u015f\u0131kl\u0131\u011f\u0131na neden olabilece\u011fini, hem de test kitlerinde hala standardizasyon sorunu oldu\u011funa dikkat \u00e7eken Prof. Dr. Erensoy, \u201cDaha da \u00f6nemlisi olu\u015fan antikorlar\u0131n ger\u00e7ek koruyuculuk d\u00fczeyi ve bunun ne kadar s\u00fcrd\u00fc\u011f\u00fc hen\u00fcz kan\u0131tlarla birlikte ortaya konmad\u0131. Bu nedenle de ki\u015filere yalanc\u0131 bir g\u00fcven hissi verebilir. Antikor test kitlerinin farkl\u0131 performanslar\u0131 olabilir, \u00e7\u00fcnk\u00fc hem vir\u00fcs\u00fcn hangi par\u00e7as\u0131na kar\u015f\u0131 antikorlar\u0131n bak\u0131ld\u0131\u011f\u0131yla ili\u015fkili olarak, hem de y\u00f6ntemlerin teknik \u00f6zelliklerine g\u00f6re de\u011fi\u015fiklikler olabilmektedir\u201d dedi.<\/p>\n

\u201cTESTLER UZMANLAR TARAFINDAN YORUMLANMALI\u201d<\/strong><\/p>\n

T\u0131bb\u0131n her alan\u0131nda \u00f6nceli\u011fin zarar vermeme ilkesi oldu\u011funu dile getiren Prof. Dr. Erensoy, tan\u0131 laboratuvarlar\u0131nda da ayn\u0131 sorumlulu\u011fun ta\u015f\u0131nd\u0131\u011f\u0131n\u0131, ortaya \u00e7\u0131kan sonu\u00e7lar\u0131n uzman\u0131 olmayan ki\u015filer taraf\u0131ndan de\u011ferlendirilmesinin istenmeyen olaylara yol a\u00e7abilece\u011fine vurgu yapt\u0131. H\u0131zl\u0131 antikor testi yapan baz\u0131 kitlerin bulundu\u011funu, ancak bu kitlerin her zaman do\u011fru sonu\u00e7 veremeyebilece\u011fini de ifade eden Prof. Dr. Erensoy, \u201cAntikor testi sonucu pozitif \u00e7\u0131ksa da bu her zaman v\u00fccudun vir\u00fcse kar\u015f\u0131 yeterli koruma sa\u011flad\u0131\u011f\u0131 anlam\u0131na gelmez. Antikor testi yapt\u0131ran ki\u015fiyi yan\u0131ltabilir. O y\u00fczden test se\u00e7imine ve kullan\u0131m alan\u0131na da konunun uzmanlar\u0131n\u0131n karar vermesi \u00f6nemli. ELISA temelli denilen ya da teknik olarak duyarl\u0131l\u0131\u011f\u0131n\u0131n daha y\u00fcksek oldu\u011fu bilinen y\u00f6ntemlerin kullan\u0131lmas\u0131 tercih ediliyor. Hastal\u0131\u011f\u0131 ge\u00e7iren ya da a\u015f\u0131 olan ki\u015finin v\u00fccudun \u00fcretti\u011fi antikor ancak 3 haftada y\u00fcksek seviyeye geliyor. En \u00f6nemlisi bu testlerle ortaya \u00e7\u0131kan antikor sonu\u00e7lar\u0131, enfeksiyondan koruma konusunda birebir kesin kan\u0131t de\u011fil\u201d diye konu\u015ftu.<\/p>\n

\u201cSONU\u00c7 NE OLURSA OLSUN KORUNMA \u00d6NLEMLER\u0130NE DEVAM ED\u0130LMEL\u0130\u201d<\/strong><\/p>\n

\"\"Enfeksiyondan koruyuculu\u011fun belirlenmesinde as\u0131l y\u00f6ntemin, h\u00fccre k\u00fclt\u00fcr\u00fcnde, vir\u00fcs\u00fcn h\u00fccrelere bula\u015fmas\u0131n\u0131 \u00f6nleyici antikorlar ya da koruyucu immun yan\u0131t\u0131n olup olmamas\u0131na bak\u0131ld\u0131\u011f\u0131 n\u00f6tralizasyon ad\u0131yla ifade edilen y\u00f6ntem oldu\u011funu belirten Prof. Dr. Erensoy, \u201cAncak bu y\u00f6ntem rutinde her laboratuvarda yap\u0131labilen bir test de\u011fil. Ayr\u0131ca antikor testi yapt\u0131ran ki\u015filerin sonu\u00e7 ne olursa olsun vir\u00fcse kar\u015f\u0131 t\u00fcm korunma y\u00f6ntemlerine ayn\u0131 \u015fekilde uymas\u0131 gerekiyor. Ki\u015filer bireysel olarak antikor testi yapt\u0131rmamal\u0131. Hekimlerin de T\u0131bbi Mikrobiyoloji uzmanlar\u0131yla ileti\u015fim halinde t\u00fcm art\u0131s\u0131 eksisiyle, testler ve sonucun ne anlamlara gelebilece\u011fi konusunda dikkatli olmas\u0131 gerekiyor\u201d dedi.<\/p>\n

\n

\n

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Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi (E\u00dcTF) T\u0131bbi Mikrobiyoloji Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi ve T\u0131bbi Viroloji Bilim…<\/p>\n","protected":false},"author":2,"featured_media":3119,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,68],"tags":[],"class_list":["post-3117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gncl","category-saglik"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4.jpg",1500,1000,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4-768x512.jpg",640,427,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4-1024x683.jpg",640,427,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4.jpg",1500,1000,false],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4.jpg",1500,1000,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4-1024x683.jpg",1024,683,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2021\/04\/Prof.-Dr.-Selda-Erensoy-_Antikor-testi-yalanci-bir-guven-hissi-verebilir_4-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"G\u00fcncel<\/a> Sa\u011fl\u0131k<\/a>","tag_info":"Sa\u011fl\u0131k","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/3117","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=3117"}],"version-history":[{"count":2,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/3117\/revisions"}],"predecessor-version":[{"id":3123,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/3117\/revisions\/3123"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/3119"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=3117"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=3117"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=3117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}