Ege \u00dcniversitesi N\u00fckleer Bilimler Enstit\u00fcs\u00fc \u00f6\u011fretim \u00fcyesi Prof. Dr. \u00c7i\u011fdem \u0130\u00e7hedef\u2019in y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 \u201cG-D\u00f6rtl\u00fc Yap\u0131lar\u0131n\u0131 Hedefleyen Naftelen Diimid ve Auger Elektron Tedavisinin Birlikte Kullan\u0131m\u0131 ile Sa\u011flanacak Kombine Tedavinin Glioblastoma H\u00fccreleri \u00dczerindeki Teranostik Etkilerinin \u0130ncelenmesi\u201d ba\u015fl\u0131kl\u0131 proje, T\u00dcB\u0130TAK 1001 program\u0131 kapsam\u0131nda desteklenmeye hak kazand\u0131.<\/p>\n
Bu proje ile y\u00fcksek \u00f6l\u00fcm oran\u0131na sahip ve olduk\u00e7a agresif seyreden glioblastoma adl\u0131 beyin t\u00fcm\u00f6r\u00fcne y\u00f6nelik yeni nesil bir teranostik ajan geli\u015ftirilmesi hedefleniyor.<\/p>\n
Proje ekibini tebrik eden Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, \u201c\u00dcniversite olarak, bilim insanlar\u0131m\u0131z\u0131n nitelikli ara\u015ft\u0131rma projeleriyle ulusal ve uluslararas\u0131 destekler almas\u0131n\u0131 son derece \u00f6nemsiyoruz. \u00d6zellikle sa\u011fl\u0131k alan\u0131nda, tan\u0131 ve tedavi s\u00fcre\u00e7lerini b\u00fct\u00fcnc\u00fcl bir \u015fekilde ele alan bu t\u00fcr projeler, hem akademik hem de toplumsal fayda a\u00e7\u0131s\u0131ndan b\u00fcy\u00fck de\u011fer ta\u015f\u0131yor. De\u011ferli hocam\u0131z Prof. Dr. \u00c7i\u011fdem \u0130\u00e7hedef\u2019i ve proje ekibini kutluyor, \u00e7al\u0131\u015fmalar\u0131nda ba\u015far\u0131lar diliyorum\u201d dedi.<\/p>\n
Proje hakk\u0131nda bilgi veren Prof. Dr. \u00c7i\u011fdem \u0130\u00e7hedef, \u201cProje kapsam\u0131nda\u00a0 Telomeraz aktivitesi y\u00fcksek olan kanser h\u00fccrelerini hedef alacak \u015fekilde, G-d\u00f6rtl\u00fc DNA yap\u0131lar\u0131yla etkile\u015fime giren Naftelen Diimid t\u00fcrevi bir molek\u00fcl\u00fc Tc-99m radyoizotopu ile i\u015faretleyerek \u00f6zg\u00fcn bir radyofarmas\u00f6tik tasarl\u0131yoruz. Tc-99m\u2019in Auger elektronlar\u0131 yaymas\u0131 sayesinde, hem g\u00f6r\u00fcnt\u00fcleme hem de tedavi \u00f6zelliklerini bir arada sunan bir yakla\u015f\u0131m geli\u015ftirece\u011fiz. Bu kompleksin, glioblastoma h\u00fccre hatt\u0131 \u00fczerinde sitotoksik ve radyotoksik etkileri in vitro olarak de\u011ferlendirilerek, sa\u011fl\u0131kl\u0131 dokulara zarar vermeden se\u00e7ici t\u00fcm\u00f6r hedeflemesi sa\u011flanacak. Ayn\u0131 zamanda Tc-99m\u2019in g\u00f6r\u00fcnt\u00fcleme potansiyeli sayesinde tedavi s\u00fcreci de izlenebilir olacak\u201d diye konu\u015ftu.<\/p>\n","protected":false},"excerpt":{"rendered":"
Ege \u00dcniversitesi N\u00fckleer Bilimler Enstit\u00fcs\u00fc \u00f6\u011fretim \u00fcyesi Prof. Dr. \u00c7i\u011fdem \u0130\u00e7hedef\u2019in y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 \u201cG-D\u00f6rtl\u00fc Yap\u0131lar\u0131n\u0131…<\/p>\n","protected":false},"author":2,"featured_media":30007,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,99,1,70],"tags":[],"class_list":["post-30006","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim","category-egitim","category-gncl","category-kampus"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak.jpg",1500,1000,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak-768x512.jpg",640,427,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak-1024x683.jpg",640,427,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak.jpg",1500,1000,false],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak.jpg",1500,1000,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak-1024x683.jpg",1024,683,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Cigdem-Ichedef_ProfDrNecdetBudak-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> E\u011fitim<\/a> G\u00fcncel<\/a> Kamp\u00fcs<\/a>","tag_info":"Kamp\u00fcs","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/30006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=30006"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/30006\/revisions"}],"predecessor-version":[{"id":30008,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/30006\/revisions\/30008"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/30007"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=30006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=30006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=30006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}