{"id":29653,"date":"2025-08-01T03:19:00","date_gmt":"2025-08-01T03:19:00","guid":{"rendered":"https:\/\/www.euegeajans.com\/?p=29653"},"modified":"2025-08-01T07:20:54","modified_gmt":"2025-08-01T07:20:54","slug":"egeli-bilim-insani-doc-dr-ekicinin-projesine-yilin-yenilikci-eczacisi-odulu","status":"publish","type":"post","link":"https:\/\/www.euegeajans.com\/index.php\/2025\/08\/01\/egeli-bilim-insani-doc-dr-ekicinin-projesine-yilin-yenilikci-eczacisi-odulu\/","title":{"rendered":"Egeli bilim insan\u0131 Do\u00e7. Dr. Ekici\u2019nin projesine “Y\u0131l\u0131n Yenilik\u00e7i Eczac\u0131s\u0131” \u00f6d\u00fcl\u00fc"},"content":{"rendered":"

Ege \u00dcniversitesi (E\u00dc) Eczac\u0131l\u0131k Fak\u00fcltesi Radyofarmasi Anabilim Dal\u0131 \u00f6\u011fretim \u00dcyesi Do\u00e7. Dr. Meliha Ekinci\u2019nin y\u00fcr\u00fct\u00fcc\u00fcs\u00fc oldu\u011fu \u201cMeme Kanserine Hedefli Lapatinib Ditosilat \u0130\u00e7eren Nano Yap\u0131l\u0131 Lipit Ta\u015f\u0131y\u0131c\u0131 Sistemlerin Geli\u015ftirilmesi ve Hedeflendirme Etkinli\u011finin\u00a0in vitro<\/em>\u00a0Olarak De\u011ferlendirilmesi\u201d adl\u0131 BAP projesi, Doktorclub Awards 2024 Y\u0131l\u0131 Sa\u011fl\u0131k Profesyoneli \u00d6d\u00fclleri kapsam\u0131nda verilen \u00a0“Y\u0131l\u0131n Yenilik\u00e7i Eczac\u0131s\u0131” kategorisinde \u00f6d\u00fcle lay\u0131k g\u00f6r\u00fcld\u00fc. Proje, yerli radyofarmas\u00f6tiklerin \u00fcretimi alan\u0131nda yap\u0131lacak Ar-Ge \u00e7al\u0131\u015fmalar\u0131, teknoloji transferinin ger\u00e7ekle\u015ftirilmesi, yat\u0131r\u0131m ve tesisle\u015fmeyle hem sa\u011fl\u0131k hem de ekonomi a\u00e7\u0131s\u0131ndan \u00fclkemizin refah d\u00fczeyine katk\u0131 sa\u011flayacak.<\/p>\n

Eczac\u0131l\u0131k Fak\u00fcltesi Radyofarmasi Anabilim Dal\u0131 \u00f6\u011fretim \u00dcyesi Do\u00e7. Dr. Meliha Ekinci\u2019yi tebrik eden Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, \u201cT\u00fcrkiye\u2019nin k\u00f6kl\u00fc, Ege B\u00f6lgesinin ilk y\u00fcksek\u00f6\u011fretim kurumu olan Ege \u00dcniversitesi, kaliteli e\u011fitim \u00f6\u011fretimi, g\u00fc\u00e7l\u00fc ara\u015ft\u0131rma geli\u015ftirme ve inovasyon altyap\u0131s\u0131, nitelikli akademik insan kayna\u011f\u0131 ile bilimsel \u00e7al\u0131\u015fmalar\u0131na devam ediyor. Tam akredite, sa\u011fl\u0131k temal\u0131, milli yenilik \u00f6d\u00fcll\u00fc ara\u015ft\u0131rma \u00fcniversitemiz \u00e7at\u0131s\u0131 alt\u0131nda g\u00f6rev yapan bilim insanlar\u0131m\u0131z\u0131n haz\u0131rlad\u0131klar\u0131 projeler ulusal ve uluslararas\u0131 alanda \u00f6d\u00fcllerle taltif ediliyor. Eczac\u0131l\u0131k Fak\u00fcltesi \u00d6\u011fretim \u00dcyesi Do\u00e7. Dr. Meliha Ekinci hocam\u0131z\u0131n BAP projesi Doktorclub Awards 2024 Y\u0131l\u0131n Sa\u011fl\u0131k Profesyoneli \u00d6d\u00fclleri’nde \u2018Y\u0131l\u0131n Yenilik\u00e7i Eczac\u0131s\u0131\u2019 kategorisinde \u00f6d\u00fcl almaya hak kazand\u0131. Hocam\u0131z\u0131 tebrik ediyor \u00e7al\u0131\u015fmalar\u0131nda ba\u015far\u0131lar diliyorum\u201d dedi.<\/p>\n

\u201cErken evrede te\u015fhise imk\u00e2n verecek\u201d<\/strong><\/p>\n

Proje hakk\u0131nda bilgi veren Ege \u00dcniversitesi Eczac\u0131l\u0131k Fak\u00fcltesi Radyofarmasi Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Do\u00e7. Dr. Meliha Ekinci, \u201cMeme kanseri, k\u00fcresel \u00e7apta kad\u0131nlarda ilk s\u0131rada g\u00f6r\u00fclen kanser t\u00fcr\u00fc oldu\u011fundan, meme kanserinin erken evrede tan\u0131s\u0131 ve etkili bir \u015fekilde tedavisi b\u00fcy\u00fck \u00f6nem ta\u015f\u0131maktad\u0131r. Radyolojik g\u00f6r\u00fcnt\u00fclemeler, morfolojik de\u011fi\u015fikliklere dayand\u0131\u011f\u0131 i\u00e7in hastal\u0131\u011f\u0131n erken evresindeki g\u00f6r\u00fcnt\u00fclemede yeterli olamamaktad\u0131r. Fakat n\u00fckleer t\u0131p g\u00f6r\u00fcnt\u00fclemeleri, fizyolojik de\u011fi\u015fikliklerin tespitine dayand\u0131\u011f\u0131ndan erken evrede te\u015fhise imk\u00e2n verecek\u201d diye konu\u015ftu.<\/p>\n

\u201cYerli ve milli yeni bir radyofarmas\u00f6tik geli\u015ftirildi\u201d<\/strong><\/p>\n

Do\u00e7. Dr. Meliha Ekinci, \u201cMeme kanseri olgular\u0131n\u0131n y\u00fczde 30\u2019unda insan epidermal b\u00fcy\u00fcme fakt\u00f6r\u00fc resept\u00f6r\u00fc 2\u2019nin (HER2) a\u015f\u0131r\u0131 derecede artt\u0131\u011f\u0131 g\u00f6r\u00fclmektedir. Bu \u00f6zellik, HER2 resept\u00f6r\u00fcn\u00fc meme t\u00fcm\u00f6r\u00fc dokusunu hedefleme amac\u0131 ile kullan\u0131labilecek muhtemel bir hedef haline getirmektedir. HER2-negatif meme kanseri ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, HER2-pozitif kanserler, genellikle daha d\u00fc\u015f\u00fck hasta sa\u011fkal\u0131m oranlar\u0131na yol a\u00e7an k\u00f6t\u00fc diferansiye ve y\u00fcksek dereceli olma e\u011filimindedir. HER2, kanser h\u00fccrelerinin hayatta kalmas\u0131nda \u00e7ok \u00f6nemli bir rol oynad\u0131\u011f\u0131ndan, k\u00fc\u00e7\u00fck molek\u00fcll\u00fc tirozin kinaz inhibit\u00f6rleri dahil olmak \u00fczere bir\u00e7ok ila\u00e7 i\u00e7in terap\u00f6tik bir hedef haline gelmi\u015ftir. Lapatinib ditosilat, HER2 pozitif metastatik meme kanserinin tedavisinde kullan\u0131lan FDA onayl\u0131 bir tirozin kinaz inhibit\u00f6r\u00fcd\u00fcr. Bu bilgiler \u0131\u015f\u0131\u011f\u0131nda proje kapsam\u0131nda, meme kanserinin erken tan\u0131s\u0131nda kullan\u0131lmak \u00fczere, HER2 resept\u00f6r\u00fcne spesifik olup hedef h\u00fccrelerde y\u00fcksek tutulum g\u00f6stererek sintigrafik ay\u0131r\u0131m\u0131n iyi, sa\u011fl\u0131kl\u0131 h\u00fccrelerdeki radyasyon hasar\u0131n\u0131n d\u00fc\u015f\u00fck oldu\u011fu, SPECT g\u00f6r\u00fcnt\u00fclemeye uygun,\u00a099m<\/sup>Tc ile i\u015faretli lapatinib ditosilat y\u00fckl\u00fc nano yap\u0131l\u0131 lipid ta\u015f\u0131y\u0131c\u0131 sistemleri i\u00e7eren, h\u00fccresel d\u00fczeyde tan\u0131 imk\u00e2n\u0131 veren yerli ve milli yeni bir radyofarmas\u00f6tik geli\u015ftirildi\u201d dedi.<\/p>\n

\u201cYerli radyofarmas\u00f6tik d\u0131\u015fa ba\u011f\u0131ml\u0131l\u0131\u011f\u0131 azaltacak\u201d<\/strong><\/p>\n

Geli\u015ftirilen\u00a0yerli radyofarmas\u00f6tikin d\u0131\u015fa ba\u011f\u0131ml\u0131l\u0131\u011f\u0131 azaltaca\u011f\u0131n\u0131 ifade eden Do\u00e7. Dr. Meliha Ekinci, \u201c\u0130la\u00e7, t\u0131bbi cihaz ve tan\u0131 kitinde yerlilik oran\u0131m\u0131z d\u0131\u015fa ba\u011f\u0131ml\u0131l\u0131k oran\u0131na k\u0131yasla daha d\u00fc\u015f\u00fck seviyededir ve bu d\u0131\u015fa ba\u011f\u0131ml\u0131l\u0131k finansal a\u00e7\u0131dan \u00fclkemize ciddi bir y\u00fck getirmektedir. Projede oldu\u011fu gibi, yerli radyofarmas\u00f6tiklerin \u00fcretimi alan\u0131nda yap\u0131lacak Ar-Ge \u00e7al\u0131\u015fmalar\u0131, teknoloji transferinin ger\u00e7ekle\u015ftirilmesi, yat\u0131r\u0131m ve tesisle\u015fmeyle hem sa\u011fl\u0131k hem de ekonomi a\u00e7\u0131s\u0131ndan \u00fclkemizin refah d\u00fczeyine katk\u0131 sa\u011flanacak\u201d diye konu\u015ftu<\/p>\n","protected":false},"excerpt":{"rendered":"

Ege \u00dcniversitesi (E\u00dc) Eczac\u0131l\u0131k Fak\u00fcltesi Radyofarmasi Anabilim Dal\u0131 \u00f6\u011fretim \u00dcyesi Do\u00e7. Dr. Meliha Ekinci\u2019nin y\u00fcr\u00fct\u00fcc\u00fcs\u00fc…<\/p>\n","protected":false},"author":2,"featured_media":29654,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,99,1,70],"tags":[],"class_list":["post-29653","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim","category-egitim","category-gncl","category-kampus"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci.jpg",1500,1000,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci-768x512.jpg",640,427,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci-1024x683.jpg",640,427,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci.jpg",1500,1000,false],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci.jpg",1500,1000,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci-1024x683.jpg",1024,683,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2025\/08\/Prof.-Dr.-Necdet-Budak-Doc.-Dr.-Meliha-Ekinci-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> E\u011fitim<\/a> G\u00fcncel<\/a> Kamp\u00fcs<\/a>","tag_info":"Kamp\u00fcs","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/29653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=29653"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/29653\/revisions"}],"predecessor-version":[{"id":29655,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/29653\/revisions\/29655"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/29654"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=29653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=29653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=29653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}