\u00a0Ege \u00dcniversitesi(E\u00dc) Eczac\u0131l\u0131k Fak\u00fcltesi doktora \u00f6\u011frencisi Yal\u00e7\u0131n \u00c7elik Ayd\u0131n\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131, Prof. Dr. Emel \u00d6yk\u00fc \u00c7etin Uyan\u0131kgil\u2019in dan\u0131\u015fmanl\u0131\u011f\u0131n\u0131 \u00fcstlendi\u011fi doktora tezi \u201cLipid bazl\u0131 nanota\u015f\u0131y\u0131c\u0131lar kullan\u0131larak diyabet tedavisinde kullan\u0131lan model bir maddenin oral biyoyararlan\u0131m\u0131n\u0131n art\u0131r\u0131lmas\u0131\u201d projesi T\u00dcB\u0130TAK “1002- B Acil Destekleme Mod\u00fcl\u00fc”\u00a0 kapsam\u0131nda destek almaya hak kazand\u0131. Proje ile diyabet hastalar\u0131n\u0131n ila\u00e7 kullan\u0131m s\u00fcresinin ve dozunun azalt\u0131larak hem hasta sa\u011fl\u0131\u011f\u0131na hem de ekonomiye katk\u0131 sunulacak.<\/p>\n
Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, Prof. Dr. Emel \u00d6yk\u00fc \u00c7etin Uyan\u0131kgil ve Yal\u00e7\u0131n \u00c7elik Ayd\u0131n\u2019\u0131 makam\u0131nda a\u011f\u0131rlayarak tebrik etti.\u00a0Rekt\u00f6r Prof. Dr. Necdet Budak, \u201cTam kurumsal akreditasyona sahip, \u00f6\u011frenci odakl\u0131l\u0131kta \u00f6d\u00fcll\u00fc, \u00f6nc\u00fc ara\u015ft\u0131rma \u00fcniversitemizde\u00a0olu\u015fturdu\u011fumuz \u00f6rnek bilim \u00fcretme ekosistemimiz b\u00fcnyesinde g\u00f6rev yapan ara\u015ft\u0131rmac\u0131lar\u0131m\u0131z\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 nitelikli projeler ulusal ve uluslararas\u0131 kurum ve kurulu\u015flardan destek g\u00f6rmeye devam ediyor. Diyabet, d\u00fcnya genelinde en yayg\u0131n olarak g\u00f6r\u00fclen kronik hastal\u0131klardan biridir. Geli\u015ftirilen projeyle diyabet tedavisi i\u00e7in ihtiya\u00e7 duyulan dozlar\u0131n azalt\u0131lmas\u0131yla ekonomik geri kazan\u0131m sa\u011flanacak. T\u00dcB\u0130TAK taraf\u0131ndan da destek g\u00f6ren bu projeyi ger\u00e7ekle\u015ftiren akademisyenlerimizi tebrik ediyorum. \u00c7al\u0131\u015fmalar\u0131nda ba\u015far\u0131lar diliyorum\u201d dedi.<\/p>\n
\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u201c\u0130la\u00e7lar\u0131n yan etkileri tedaviyi de olumsuz etkiliyor\u201d<\/b><\/p>\n
\u00a0<\/b>Diyabete yakalanan bireylerin tedavisinin \u00f6m\u00fcr boyu s\u00fcrd\u00fc\u011f\u00fcn\u00fc s\u00f6yleyen Doktora \u00f6\u011frencisi Yal\u00e7\u0131n \u00c7elik Ayd\u0131n, \u201cDiyabet d\u00fcnya genelinde en yayg\u0131n olarak g\u00f6r\u00fclen kronik hastal\u0131klardan biridir. Tam anlam\u0131yla tedavi sa\u011flanarak geri d\u00f6nd\u00fcr\u00fclmesi hen\u00fcz ke\u015ffedilemedi\u011fi i\u00e7in bir kere diyabet hastas\u0131 olan bir ki\u015finin tedavisi t\u00fcm \u00f6mr\u00fc boyunca s\u00fcrmektedir. Bu durum hem hastalar\u0131n ila\u00e7 kullan\u0131m s\u00fcrelerini ve dozunu art\u0131r\u0131rken hem de sa\u011fl\u0131k sistemine giderek b\u00fcy\u00fcyen bir y\u00fck bindirmektedir. Diyabetin tedavisinde ve obeziteye ba\u011fl\u0131 diyabetin \u00f6nlenmesinde kullan\u0131lan \u2018liraglutid\u2019 ile \u2018berberin\u2019 d\u00fc\u015f\u00fck biyoyararlan\u0131m g\u00f6steren iki \u00f6nemli etkin maddedir. G\u00f6sterdikleri d\u00fc\u015f\u00fck oral biyoyararlan\u0131m sebebiyle g\u00fcn\u00fcm\u00fczde berberin oral olarak y\u00fcksek dozlarda, liraglutid ise enjeksiyon y\u00f6ntemi ile kullanmaktad\u0131r. Subk\u00fctan kullan\u0131m yolunun ve oral olarak kullan\u0131lan y\u00fcksek dozlar\u0131n do\u011fal bir sonucu ise istenmeyen etkilerin de bu ila\u00e7lar\u0131n kullan\u0131mlar\u0131 s\u0131ras\u0131nda s\u0131kl\u0131kla g\u00f6r\u00fclmesidir. \u0130la\u00e7lara ba\u011fl\u0131 olarak g\u00f6r\u00fclen istenmeyen etkiler, hastalar\u0131n bu istenmeyen etkileri bask\u0131lamak i\u00e7in ba\u015fka ila\u00e7lar\u0131 da kullanmalar\u0131na veya ila\u00e7lar\u0131 d\u00fczensiz kullanmaya ve hatta kullanmay\u0131 b\u0131rakmalar\u0131na sebep olmaktad\u0131r. Bu durum da tedavinin aksamas\u0131na ve hastalarda ikincil ba\u015fka hastal\u0131klar\u0131n g\u00f6r\u00fclmesine zemin haz\u0131rlamaktad\u0131r\u201d diye konu\u015ftu.<\/p>\n
\u201cEkonomik olarak kazan\u0131m sa\u011flanacak\u201d<\/b><\/p>\n
Tedavi i\u00e7in ihtiya\u00e7 duyulan dozlar\u0131n azalmas\u0131na ba\u011fl\u0131 olarak ekonomik geri kazan\u0131m da sa\u011flanaca\u011f\u0131n\u0131 vurgulayan Yal\u00e7\u0131n \u00c7elik Ayd\u0131n, \u201cYeni nesil ila\u00e7 ta\u015f\u0131y\u0131c\u0131 sistemler kullan\u0131larak oral biyoyararlan\u0131m\u0131n art\u0131r\u0131lmas\u0131 ve istenmeyen etkilerin azalt\u0131lmas\u0131 son y\u0131llarda s\u0131kl\u0131kla kullan\u0131lan bir y\u00f6ntemdir. Bu sayede \u00e7ok daha az istenmeyen etki g\u00f6r\u00fclmesi sa\u011flanarak hasta uyuncu y\u00fckseltilir ve tedavinin sa\u011fl\u0131kl\u0131 bir \u015fekilde s\u00fcrd\u00fcr\u00fclmesi sa\u011flan\u0131r. Art\u0131r\u0131lan oral biyoyararlan\u0131m\u0131n ikincil bir etkisi ise tedavi i\u00e7in ihtiya\u00e7 duyulan dozlar\u0131n azalmas\u0131na ba\u011fl\u0131 olarak sa\u011flanan ekonomik geri kazan\u0131md\u0131r. Proje \u00e7al\u0131\u015fmalar\u0131m\u0131 y\u00fcr\u00fct\u00fcrken her zaman yan\u0131mda olan dan\u0131\u015fman hocam Prof. Dr. Emel \u00d6yk\u00fc \u00c7etin Uyan\u0131kgil\u2019e \u00e7ok te\u015fekk\u00fcr ederim\u201d dedi.<\/p>\n","protected":false},"excerpt":{"rendered":"
\u00a0Ege \u00dcniversitesi(E\u00dc) Eczac\u0131l\u0131k Fak\u00fcltesi doktora \u00f6\u011frencisi Yal\u00e7\u0131n \u00c7elik Ayd\u0131n\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131, Prof. Dr. Emel \u00d6yk\u00fc…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,99,1,70],"tags":[],"class_list":["post-25179","post","type-post","status-publish","format-standard","hentry","category-bilim","category-egitim","category-gncl","category-kampus"],"featured_image_urls":{"full":"","thumbnail":"","medium":"","medium_large":"","large":"","1536x1536":"","2048x2048":"","newsphere-slider-full":"","newsphere-featured":"","newsphere-medium":""},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> E\u011fitim<\/a> G\u00fcncel<\/a> Kamp\u00fcs<\/a>","tag_info":"Kamp\u00fcs","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/25179","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=25179"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/25179\/revisions"}],"predecessor-version":[{"id":25181,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/25179\/revisions\/25181"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=25179"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=25179"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=25179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}