Ege \u00dcniversitesi Fen Fak\u00fcltesi Biyokimya B\u00f6l\u00fcm\u00fc \u00f6\u011fretim \u00fcyesi Prof. Dr. Serap Evran\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 \u201cMycobacterium tuberculosis Vir\u00fclans Fakt\u00f6r\u00fc Zmp\u2019\u0131n Enzimatik Aktivitesinin Se\u00e7imli \u0130nhibisyonu \u0130\u00e7in DNA Aptamerinin Geli\u015ftirilmesi\u201d ba\u015fl\u0131kl\u0131 proje, T\u00dcB\u0130TAK 1001 Bilimsel ve Teknolojik Ara\u015ft\u0131rma Projelerini Destekleme Program\u0131 kapsam\u0131nda desteklenmeye uygun bulundu. Proje ile verem hastal\u0131\u011f\u0131nda antibiyotik direncini engelleyen bir inhib\u00fct\u00f6r geli\u015ftirilecek.<\/p>\n
Proje ekibini tebrik eden Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, \u201c\u00dcniversitemiz, \u00f6zellikle sa\u011fl\u0131k alan\u0131nda geli\u015ftirdi\u011fi projeler ile T\u00fcrkiye\u2019de ve d\u00fcnyada adeta bir referans merkezi konumunda. Sa\u011fl\u0131k alan\u0131ndaki projeleriniz, T\u00dcB\u0130TAK nezdinde de kabul g\u00f6rmeye devam ediyor. Fen Fak\u00fcltesi Biyokimya B\u00f6l\u00fcm\u00fc \u00f6\u011fretim \u00fcyemiz Prof. Dr. Serap Evran ve ekibi, verem hastal\u0131\u011f\u0131n\u0131n tedavisinde \u00f6nemli bir sorun olan antibiyotik direncinin a\u015f\u0131lmas\u0131na katk\u0131 sa\u011flayacak \u00f6nemli bir projeye imza at\u0131yorlar. Hocam\u0131z\u0131 ve ekibini kutluyor, ba\u015far\u0131lar\u0131n\u0131n\u00a0 devam\u0131n\u0131 diliyorum\u201d dedi.<\/p>\n
T\u00fcberk\u00fcloz hastal\u0131\u011f\u0131n\u0131n \u00f6l\u00fcmc\u00fcl bir nitelik ta\u015f\u0131d\u0131\u011f\u0131n\u0131 ifade eden Prof. Dr. Serap Evran, \u201cT\u00fcberk\u00fcloz (verem) her y\u0131l yakla\u015f\u0131k 2 milyon ki\u015finin \u00f6l\u00fcm\u00fcne neden olan bula\u015f\u0131c\u0131 bir hastal\u0131kt\u0131r. T\u00fcberk\u00fcloz kaynakl\u0131 \u00f6l\u00fcmlerin \u00f6nlenmesi, Birle\u015fmi\u015f Milletler S\u00fcrd\u00fcr\u00fclebilir Kalk\u0131nma Ama\u00e7lar\u0131n\u0131n sa\u011fl\u0131k hedeflerinden de birisidir. T\u00fcberk\u00fcloza\u00a0\u2018Mycobacterium tuberculosis\u2019\u00a0bakterisi neden olur ve tedavide antibiyotikler kullan\u0131l\u0131r. Ancak, bakterinin antibiyoti\u011fe kar\u015f\u0131 diren\u00e7 kazanmas\u0131 tedaviyi zorla\u015ft\u0131ran bir fakt\u00f6r. Bu nedenle, bakterinin diren\u00e7 g\u00f6stermedi\u011fi yeni ila\u00e7lar\u0131n ke\u015ffine ihtiya\u00e7 var. Projemizde, antibiyotik direnci sorununa kar\u015f\u0131 farkl\u0131 bir yakla\u015f\u0131m kullanmay\u0131 hedefliyoruz. Ba\u011f\u0131\u015f\u0131kl\u0131k sistemimiz t\u00fcberk\u00fcloza neden olan bakteriye kar\u015f\u0131 bir cevap olu\u015fturuyor. Ancak, bakteri Zmp ad\u0131 verilen bir enzimi \u00fcreterek ba\u011f\u0131\u015f\u0131kl\u0131k sisteminden ka\u00e7abiliyor. Projedeki amac\u0131m\u0131z, bu enzimin aktivite g\u00f6stermesini engelleyen aptamer yap\u0131l\u0131 bir inhibit\u00f6r geli\u015ftirmek\u201d diye konu\u015ftu.<\/p>\n
\u201cYeni nesil antibiyotikler geli\u015ftirilecek\u201d<\/strong><\/p>\n Prof. Dr. Evran, \u201cProjemizden elde edece\u011fimiz sonu\u00e7lar, Rekt\u00f6r\u00fcm\u00fcz Prof. Dr. Necdet Budak taraf\u0131ndan olu\u015fturulan multidisipliner \u2018Aptamer Tabanl\u0131 Yeni-nesil Antimikrobiyaller \u00c7al\u0131\u015fma Grubu\u2019 \u00fcyelerinin katk\u0131lar\u0131yla yeni projelerin \u00fcretilmesini sa\u011flayabilecek. Temel bilim d\u00fczeyinde yapaca\u011f\u0131m\u0131z bu ara\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131n\u0131 t\u0131p ve eczac\u0131l\u0131k alanlar\u0131nda \u00e7al\u0131\u015fan ara\u015ft\u0131rmac\u0131lar ile payla\u015farak yeni-nesil antibiyotiklerin geli\u015ftirilmesine katk\u0131 sa\u011flamay\u0131 hedefliyoruz\u201d dedi.<\/p>\n Proje ekibinde Prof. Dr. Serap Evran\u2019\u0131n yan\u0131 s\u0131ra ara\u015ft\u0131rmac\u0131 olarak Ege \u00dcniversitesi Fen Fak\u00fcltesi Biyokimya B\u00f6l\u00fcm\u00fc\u2019nden \u00d6\u011fr. G\u00f6r. Dr. Burhan Bora yer al\u0131yor.<\/p>\n","protected":false},"excerpt":{"rendered":" Ege \u00dcniversitesi Fen Fak\u00fcltesi Biyokimya B\u00f6l\u00fcm\u00fc \u00f6\u011fretim \u00fcyesi Prof. Dr. Serap Evran\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 \u201cMycobacterium…<\/p>\n","protected":false},"author":2,"featured_media":24845,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,99,1,11,70,68],"tags":[],"class_list":["post-24844","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim","category-egitim","category-gncl","category-haber","category-kampus","category-saglik"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee.jpg",1500,1000,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee-768x512.jpg",640,427,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee-1024x683.jpg",640,427,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee.jpg",1500,1000,false],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee.jpg",1500,1000,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee-1024x683.jpg",1024,683,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/12\/Prof-Dr-Serap-Evran-Projee-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> E\u011fitim<\/a> G\u00fcncel<\/a> Haber<\/a> Kamp\u00fcs<\/a> Sa\u011fl\u0131k<\/a>","tag_info":"Sa\u011fl\u0131k","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/24844","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=24844"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/24844\/revisions"}],"predecessor-version":[{"id":24846,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/24844\/revisions\/24846"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/24845"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=24844"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=24844"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=24844"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}