Zat\u00fcrreye sebep olan mikroorganizma erken te\u015fhis edilecek<\/p>\n
Ege \u00dcniversitesi akademisyenleri taraf\u0131ndan y\u00fcr\u00fct\u00fclen proje ile \u00f6zellikle ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 d\u00fc\u015f\u00fck hastalarda ciddi pn\u00f6moni (zat\u00fcrre) sebebi olan \u201cPneumocystis jirovecii\u201d adl\u0131 mikroorganizman\u0131n tan\u0131s\u0131na y\u00f6nelik h\u0131zl\u0131 test geli\u015ftirilecek. \u00d6zellikle organ nakli hastalar\u0131, kanser tedavisi g\u00f6ren hastalar ve HIV hastalar\u0131 gibi imm\u00fcn sistemi bask\u0131lanm\u0131\u015f bireylerde ciddi sa\u011fl\u0131k sorunlar\u0131na yol a\u00e7an mikroorganizman\u0131n tan\u0131s\u0131na y\u00f6nelik geli\u015ftirilen ve y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi Parazitoloji Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya\u2019n\u0131n yapt\u0131\u011f\u0131 \u201c<\/strong>Pneumocystis jirovecii tan\u0131s\u0131 i\u00e7in h\u0131zl\u0131 kolorimetrik LAMP testinin geli\u015ftirilmesi\u201d projesi, T\u00fcrkiye Sa\u011fl\u0131k Enstit\u00fcleri Ba\u015fkanl\u0131\u011f\u0131 (T\u00dcSEB) taraf\u0131ndan desteklenmeye uygun g\u00f6r\u00fcld\u00fc. Proje ekibini tebrik eden Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, \u201cEge \u00dcniversitesi olarak \u00f6zellikle sa\u011fl\u0131k alan\u0131nda yapt\u0131\u011f\u0131m\u0131z \u00e7al\u0131\u015fmalarla \u00f6ne \u00e7\u0131kmaya devam ediyoruz. Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya hocam\u0131z\u0131n ve ekibinin geli\u015ftirdikleri proje sonucunda ortaya \u00e7\u0131kacak olan test, ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 d\u00fc\u015f\u00fck hastalara kar\u015f\u0131 tehlike arz eden mikroorganizman\u0131n erken tan\u0131s\u0131nda \u00f6nemli rol oynayacak. Hocam\u0131z\u0131 ve ekibini tebrik ediyor, ba\u015far\u0131lar\u0131n\u0131n devam\u0131n\u0131 diliyorum\u201d dedi.<\/p>\n \u201cHem kolay uygulanabilir hem maliyeti d\u00fc\u015f\u00fck\u201d<\/strong><\/p>\n Projenin amac\u0131n\u0131 anlatan Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya, \u201cSolunum sistemi \u00f6rneklerinde, P. jirovecii\u2019nin rutin k\u00fclt\u00fcr\u00fc yap\u0131lamamas\u0131 sebebiyle hastal\u0131k etkeninin te\u015fhisinde yayma preparat boyama metotlar\u0131, immunfloresan boyama teknikleri ve polimeraz zincir reaksiyonu (PZR) gibi farkl\u0131 y\u00f6ntemler kullan\u0131lmaktad\u0131r. Ancak kesin tan\u0131 i\u00e7in kullan\u0131lan PZR testlerinin pahal\u0131 olmas\u0131, geli\u015fmi\u015f laboratuvar ekipmanlar\u0131 ve deneyimli personele ihtiya\u00e7 duyulmas\u0131 nedeniyle hastal\u0131\u011f\u0131n tan\u0131s\u0131nda kullan\u0131labilecek y\u00fcksek hassasiyete sahip, kolay uygulanabilir ve maliyet etkin tan\u0131 testlerine ihtiya\u00e7 duyulmaktad\u0131r. Bu sebeple patojenlerin tespitinde y\u00fcksek duyarl\u0131l\u0131k ve \u00f6zg\u00fcll\u00fck de\u011ferlerine sahip Loop-mediated isothermal amplification (LAMP) testi kullan\u0131labilmektedir. Di\u011fer molek\u00fcler testlerde gerekli olan \u0131s\u0131 de\u011fi\u015fkenliklerinin gerekmedi\u011fi bu testte olu\u015fan reaksiyon kolorimetrik yakla\u015f\u0131mlarla (renk de\u011fi\u015fimi) de\u011ferlendirilebilmektir. Saha ko\u015fullar\u0131nda ve basit laboratuvarlarda kolayl\u0131kla uygulanabildi\u011finden g\u00fcn\u00fcm\u00fczde tercih edilen bir tan\u0131 yakla\u015f\u0131m\u0131 haline gelmi\u015ftir. Bu projede solunum sistemi \u00f6rneklerinde PcP tan\u0131s\u0131 i\u00e7in y\u00fcksek hassasiyetli ve yenilik\u00e7i bir \u2018H\u0131zl\u0131-PcP-Kolorimetrik LAMP\u2019 testi geli\u015ftirilmesi ama\u00e7lanm\u0131\u015ft\u0131r\u201d dedi. Y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc ayn\u0131 zamanda Ege \u00dcniversitesi A\u015f\u0131 Geli\u015ftirme Uygulama ve Ara\u015ft\u0131rma Merkezi Ara\u015ft\u0131rmac\u0131lar\u0131 ve E\u00dc Sa\u011fl\u0131k Bilimleri Enstit\u00fcs\u00fc A\u015f\u0131 \u00c7al\u0131\u015fmalar\u0131 ABD \u00d6\u011fretim \u00dcyeleri aras\u0131nda da yer alan Do\u00e7. Dr. Aysu De\u011firmenci D\u00f6\u015fkaya\u2019n\u0131n yapt\u0131\u011f\u0131 proje ekibinde; Prof. Dr. A. Y\u00fcksel G\u00fcr\u00fcz, Prof. Dr. Cemal \u00dcn, Prof. Dr. Mert D\u00f6\u015fkaya, Do\u00e7. Dr. H\u00fcseyin Can, Do\u00e7. Dr. Muhammet Karakavuk, doktora \u00f6\u011frencisi Tu\u011fba Karakavuk yer al\u0131rken, \u00a0Ceren G\u00fcl ve \u0130rem Yavuz isimli lisans\u00fcst\u00fc \u00f6\u011frenciler de bursiyer olarak g\u00f6rev al\u0131yor.<\/p>\n \n \n \u00a0<\/strong><\/p>\n \n","protected":false},"excerpt":{"rendered":" Zat\u00fcrreye sebep olan mikroorganizma erken te\u015fhis edilecek Ege \u00dcniversitesi akademisyenleri taraf\u0131ndan y\u00fcr\u00fct\u00fclen proje ile \u00f6zellikle…<\/p>\n","protected":false},"author":2,"featured_media":22821,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,99,1,11,68],"tags":[],"class_list":["post-22820","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim","category-egitim","category-gncl","category-haber","category-saglik"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor.jpg",1500,1000,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor-300x200.jpg",300,200,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor-768x512.jpg",640,427,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor-1024x683.jpg",640,427,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor.jpg",1500,1000,false],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor.jpg",1500,1000,false],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor-1024x683.jpg",1024,683,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/08\/Egeli-akademisyenler-bagisikligi-baskilanmis-hastalarda-riskli-mikroorganizmaya-karsi-tani-testi-gelistiriyor-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> E\u011fitim<\/a> G\u00fcncel<\/a> Haber<\/a> Sa\u011fl\u0131k<\/a>","tag_info":"Sa\u011fl\u0131k","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/22820","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=22820"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/22820\/revisions"}],"predecessor-version":[{"id":22822,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/22820\/revisions\/22822"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/22821"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=22820"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=22820"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=22820"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}