\u00a0Egeli bilim ekibinden nadir hastal\u0131klar ve meme kanserinin tedavisine y\u00f6nelik proje<\/p>\n
\u00a0<\/b>Bu proje ile en agresif kanser t\u00fcrlerinin tedavisine y\u00f6nelik yenilik\u00e7i ta\u015f\u0131y\u0131c\u0131 sistemler tasarlanacak<\/b><\/p>\n
Y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc Ege \u00dcniversitesi Eczac\u0131l\u0131k Fak\u00fcltesi \u00f6\u011fretim \u00fcyesi Do\u00e7. Dr. Hasan Akbaba\u2019n\u0131n yapt\u0131\u011f\u0131 “Hedeflenebilir nanopartik\u00fcler sistemler ile \u00fc\u00e7l\u00fc negatif meme kanserine kar\u015f\u0131 CRISPR\/Cas9 arac\u0131l\u0131 Lipocalin-2 gen nakavt\u0131n\u0131n terap\u00f6tik etkinli\u011finin in vitro de\u011ferlendirilmesi” ba\u015fl\u0131kl\u0131 proje T\u00fcrkiye Sa\u011fl\u0131k Enstit\u00fcleri Ba\u015fkanl\u0131\u011f\u0131 (TU\u0308SEB) Ara\u015ft\u0131rma ve Geli\u015ftirme Projelerini\u0307 Destekleme Program\u0131 kapsam\u0131nda desteklenmeye hak kazand\u0131.<\/p>\n
Proje ekibini makam\u0131nda a\u011f\u0131rlayan Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, yapt\u0131klar\u0131 nitelikli \u00e7al\u0131\u015fmalar\u0131ndan dolay\u0131 proje ekibini tebrik ederek \u00e7al\u0131\u015fmalar\u0131nda ba\u015far\u0131lar diledi. Rekt\u00f6r Prof. Dr. Necdet Budak, \u201c\u00dcniversitemiz bilim insanlar\u0131,\u00a0 \u00fclkemiz ba\u015fta olmak \u00fczere t\u00fcm insanl\u0131\u011f\u0131n ihtiya\u00e7lar\u0131 do\u011frultusunda ara\u015ft\u0131rma alanlar\u0131n\u0131 yo\u011funla\u015ft\u0131rarak, ulusal ve uluslararas\u0131 i\u015f birlikli ve\u00a0 disiplinleraras\u0131\u00a0 \u00f6nemli projeler haz\u0131rlamaya devam ediyorlar. \u00dclkemizin uluslararas\u0131 kalite standartlar\u0131nda, referans g\u00f6sterilen\u00a0 ara\u015ft\u0131rma \u00fcniversitesi ekosisteminde\u00a0 katma de\u011fer yaratabilecek nitelikte, yenilik\u00e7i, Ar-Ge ve inovasyon \u00e7al\u0131\u015fmalar y\u00fcr\u00fcten ekibimizi y\u00fcrekten kutluyorum\u201d dedi.<\/p>\n
Y\u00fcr\u00fct\u00fclen ara\u015ft\u0131rman\u0131n detaylar\u0131 ile ilgili bilgi veren Do\u00e7. Dr. Hasan Akbaba, \u201cSon y\u0131llar\u0131n g\u00fcncel ara\u015ft\u0131rma konular\u0131ndan\u00a0gen terapisi, nadir hastal\u0131klar yan\u0131 s\u0131ra kemoterapiye ve hedeflenebilir tedavilere istenilen d\u00fczeyde yan\u0131t vermeyen kanser t\u00fcrleri i\u00e7in de alternatif bir tedavi yakla\u015f\u0131m\u0131 olmaya ba\u015flam\u0131\u015ft\u0131r. Bu hastal\u0131klardan \u00fc\u00e7l\u00fc negatif meme kanseri (TNBC), t\u00fcm meme kanserlerinin y\u00fczde 12-20’sini olu\u015fturmaktad\u0131r. Daha agresif t\u00fcm\u00f6r ilerlemesi ve k\u00f6t\u00fc bir prognozla\u00a0kendini g\u00f6steren TNBC i\u00e7in gen tedavisi umut vaat eden yenilik\u00e7i bir tedavi yakla\u015f\u0131m\u0131d\u0131r. \u00a0Proje \u00f6nerisinde hedef olarak,\u00a0TNBC’nin geli\u015fimi ve ilerlemesinde rol oynad\u0131\u011f\u0131\u00a0ispatlanm\u0131\u015f\u00a0\u00f6nemli bir onkogen olan\u00a0Lipokalin 2 (LCN2) belirlenmi\u015ftir.\u00a0Bu \u015fekilde en agresif kanser t\u00fcrlerinden biri olan TNBC\u2019de kullan\u0131lmak \u00fczere anti-proliferatif, kanser dokusuna hedeflenebilir, LCN-2 proteinine \u00f6zel olarak tasarlanm\u0131\u015f CRISPR\/Cas9 sistemi arac\u0131l\u0131\u011f\u0131 ile LCN-2 gen ifadesini kal\u0131c\u0131 bir \u015fekilde nakavt eden yenilik\u00e7i ta\u015f\u0131y\u0131c\u0131 sistemler multidisipliner bir \u00e7al\u0131\u015fman\u0131n sonunda ilk kez \u00fclkemizde tasarlanacak ve etkinlikleri ortaya konacakt\u0131r\u201d diye konu\u015ftu.<\/p>\n
Ege \u00dcniversitesi Eczac\u0131l\u0131k Fak\u00fcltesi Farmas\u00f6tik Biyoteknoloji Anabilim Dal\u0131 \u00f6\u011fretim \u00fcyesi Do\u00e7. Dr. Hasan Akbaba\u2019n\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 projede Prof. Dr. \u015eerik \u015eent\u00fcrk ve Do\u00e7. Dr. G\u00fcl\u015fah Erel Akbaba ara\u015ft\u0131rmac\u0131, Prof. Dr. A. G\u00fclten Kantarc\u0131 ise proje dan\u0131\u015fman\u0131 olarak g\u00f6rev al\u0131yor.<\/p>\n","protected":false},"excerpt":{"rendered":"
\u00a0Egeli bilim ekibinden nadir hastal\u0131klar ve meme kanserinin tedavisine y\u00f6nelik proje \u00a0Bu proje ile en…<\/p>\n","protected":false},"author":2,"featured_media":19984,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[99,1,70,68],"tags":[],"class_list":["post-19983","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-egitim","category-gncl","category-kampus","category-saglik"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA.jpg",2484,1946,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-300x235.jpg",300,235,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-768x602.jpg",640,502,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-1024x802.jpg",640,501,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-1536x1203.jpg",1536,1203,true],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-2048x1604.jpg",2048,1604,true],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-1024x802.jpg",1024,802,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/03\/PROF.-DR.-NECDET-BUDAK-DOC.-DR.-HASAN-AKBABA-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"E\u011fitim<\/a> G\u00fcncel<\/a> Kamp\u00fcs<\/a> Sa\u011fl\u0131k<\/a>","tag_info":"Sa\u011fl\u0131k","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/19983","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=19983"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/19983\/revisions"}],"predecessor-version":[{"id":19985,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/19983\/revisions\/19985"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/19984"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=19983"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=19983"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=19983"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}