E\u00dc Eczac\u0131l\u0131k Fak\u00fcltesi akademisyenlerinin projeleri T\u00dcB\u0130TAK\u2019tan destek almaya devam ediyor<\/p>\n
\u00a0Egeli bilim ekibi \u00e7ocuklarda g\u00f6r\u00fclen obezite vakalar\u0131ndaki art\u0131\u015f\u0131n nedenini ara\u015ft\u0131racak<\/b><\/p>\n
\u00a0<\/b>Y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc Ege \u00dcniversitesi Eczac\u0131l\u0131k Fak\u00fcltesi Farmas\u00f6tik Toksikoloji Anabilim Dal\u0131 \u00f6\u011fretim \u00fcyesi Prof. Dr. Hande G\u00fcrer -Orhan\u2019\u0131n yapt\u0131\u011f\u0131 \u201cAnne Karn\u0131nda Maruz Kal\u0131nan Parasetamol\u00fcn Potansiyel Obezojenik Etkisinin G\u00f6stergesi Olarak Lipidomik Profildeki De\u011fi\u015fikliklerin Ara\u015ft\u0131r\u0131lmas\u0131\u201d ba\u015fl\u0131kl\u0131 proje T\u00dcB\u0130TAK taraf\u0131ndan desteklenmeye uygun bulundu.<\/p>\n
Proje ekibini makam\u0131nda a\u011f\u0131rlayan Ege \u00dcniversitesi Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak, yapt\u0131klar\u0131 nitelikli \u00e7al\u0131\u015fmalar\u0131ndan dolay\u0131 proje ekibini tebrik ederek \u00e7al\u0131\u015fmalar\u0131nda ba\u015far\u0131lar diledi. Rekt\u00f6r Prof. Dr. Necdet Budak, \u201c\u00dcniversitemiz bilim insanlar\u0131, \u00fclkemiz ba\u015fta olmak \u00fczere t\u00fcm insanl\u0131\u011f\u0131n ihtiya\u00e7lar\u0131 do\u011frultusunda ara\u015ft\u0131rma alanlar\u0131n\u0131 yo\u011funla\u015ft\u0131rarak, ulusal ve uluslararas\u0131 i\u015f birlikli ve disiplinleraras\u0131 \u00f6nemli projeler haz\u0131rlamaya devam ediyorlar. Geli\u015fmi\u015f ve geli\u015fmekte olan \u00fclkelerin en g\u00fcncel sa\u011fl\u0131k sorunlar\u0131 aras\u0131nda yer alan; genetik, \u00e7evresel, biyolojik, sosyok\u00fclt\u00fcrel ve davran\u0131\u015fsal fakt\u00f6rlerin bir araya gelmesiyle ortaya \u00e7\u0131kan obeziteye y\u00f6nelik haz\u0131rlad\u0131klar\u0131 proje dolay\u0131s\u0131yla Eczac\u0131l\u0131k Fak\u00fcltesi Dekan\u0131 Prof. Dr. Hande G\u00fcrer Orhan hocam\u0131z\u0131 ve proje ekibini tebrik ediyorum\u201d dedi.<\/p>\n
Ara\u015ft\u0131rman\u0131n i\u00e7eri\u011fi ile ilgili bilgi veren Prof. Dr. Hande G\u00fcrer- Orhan, \u201c1975 y\u0131l\u0131ndan bu yana d\u00fcnyada obezite oran\u0131 yakla\u015f\u0131k \u00fc\u00e7 kat\u0131na \u00e7\u0131karak, g\u00fcn\u00fcm\u00fczde ciddi bir global sa\u011fl\u0131k sorunu haline gelmi\u015ftir. \u00c7ocuklarda g\u00f6r\u00fclen obezite vakalar\u0131ndaki dramatik art\u0131\u015f\u0131n sadece al\u0131nan ve harcanan enerjinin dengesizli\u011fi ve genetik fakt\u00f6rler ile a\u00e7\u0131klanamayaca\u011f\u0131, temas edilen kimyasallar\u0131n da bu etkide rol\u00fc olabilece\u011fi d\u00fc\u015f\u00fcn\u00fclmektedir. \u00c7o\u011funlukla end\u00fcstriyel kimyasallar bu etki y\u00f6n\u00fcnden su\u00e7lan\u0131yor olsa da ara\u015ft\u0131rma grubumuz anne karn\u0131nda maruz kal\u0131nan ila\u00e7lar\u0131n da ileri ya\u015flarda obezojenik etkiler do\u011furabilece\u011fi hipotezini ileri s\u00fcrerek ara\u015ft\u0131rmaya ba\u015flam\u0131\u015ft\u0131r. H\u00e2lihaz\u0131rda y\u00fcr\u00fcmekte olan T\u00dcB\u0130TAK 1001 projemizin verilerini destekleyici ve g\u00fc\u00e7lendirici olaca\u011f\u0131na inanarak ba\u015fvurdu\u011fumuz ve kabul alan bu T\u00dcB\u0130TAK projemiz kapsam\u0131nda anne karn\u0131nda parasetamole maruz kalan farelerde bu ilac\u0131n obezojenik etkisinin obezojenik etkinin erken g\u00f6stergesi olarak lipit profili \u00fczerinde olu\u015fturabilece\u011fi de\u011fi\u015fikliklerin lipidomik analizi ile ara\u015ft\u0131r\u0131lmas\u0131 planlanm\u0131\u015ft\u0131r. Bununla birlikte obezitenin erken evre g\u00f6stergesi olacak molek\u00fcler baz\u0131 de\u011fi\u015fikliklerin ara\u015ft\u0131r\u0131lmas\u0131 ve anne karn\u0131nda parasetamole maruz kalan farelerde lipit profilinde de\u011fi\u015fiklik g\u00f6r\u00fclmesi durumunda bu ilac\u0131n advers etkisinin ortaya konmas\u0131 ve \u201cSa\u011fl\u0131kl\u0131 Bireyler\u201d Birle\u015fmi\u015f Milletler S\u00fcrd\u00fcr\u00fclebilir Kalk\u0131nma Hedefine y\u00f6nelik veri elde edilmesi ama\u00e7lanm\u0131\u015ft\u0131r.\u201d dedi.<\/p>\n
Prof. Dr. Hande G\u00fcrer-Orhan\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131 projede doktora sonras\u0131 ara\u015ft\u0131rmac\u0131 olarak Dr. Bita Entezari ve ara\u015ft\u0131rmac\u0131 olarak Hacettepe \u00dcniversitesi Eczac\u0131l\u0131k Fak\u00fcltesi \u00f6\u011fretim \u00fcyesi Prof. Dr. Suna Sabuncuo\u011flu da \u00a0g\u00f6rev al\u0131yor.<\/p>\n","protected":false},"excerpt":{"rendered":"
E\u00dc Eczac\u0131l\u0131k Fak\u00fcltesi akademisyenlerinin projeleri T\u00dcB\u0130TAK\u2019tan destek almaya devam ediyor \u00a0Egeli bilim ekibi \u00e7ocuklarda g\u00f6r\u00fclen…<\/p>\n","protected":false},"author":2,"featured_media":19577,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,99,1,70],"tags":[],"class_list":["post-19576","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim","category-egitim","category-gncl","category-kampus"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-scaled.jpg",2560,1884,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-300x221.jpg",300,221,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-768x565.jpg",640,471,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-1024x753.jpg",640,471,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-1536x1130.jpg",1536,1130,true],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-2048x1507.jpg",2048,1507,true],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-1024x753.jpg",1024,753,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2024\/02\/PROF.-DR.-HANDE-GURER-ORHAN-PROF.DR_.-NECDET-BUDAK-DR.-BITA-ENTEZARI-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> E\u011fitim<\/a> G\u00fcncel<\/a> Kamp\u00fcs<\/a>","tag_info":"Kamp\u00fcs","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/19576","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=19576"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/19576\/revisions"}],"predecessor-version":[{"id":19578,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/19576\/revisions\/19578"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/19577"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=19576"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=19576"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=19576"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}