Ege \u00dcniversitesi T\u0131p Fak\u00fcltesinde g\u00f6rev yapan bilim insanlar\u0131, g\u0131da end\u00fcstrisinde s\u0131k\u00e7a kullan\u0131lan, halk aras\u0131nda sofra \u015fekeri ya da beyaz \u015feker olarak da bilinen rafine \u015fekerin h\u00fccre d\u00fczeyinde ya\u015flanmaya etkisini ara\u015ft\u0131racak. D\u00fcnyada rafine \u015fekerin genetik ve epigenetik \u00fczerinden ya\u015flanmaya etkilerini ara\u015ft\u0131ran ilk proje, Egeli bilim ekibi taraf\u0131ndan haz\u0131rland\u0131. Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi T\u0131bbi Genetik Anabilim Dal\u0131 Ba\u015fkan\u0131 Prof. Dr. Haluk Ak\u0131n\u2019\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc yapt\u0131\u011f\u0131, \u201cSprague Dawley S\u0131\u00e7anlarda Glukoz ve Fruktozun Uzun S\u00fcreli Birlikte Kullan\u0131m\u0131n\u0131n Ya\u015flanma \u0130li\u015fkili Yolaklarda Meydana Getirdi\u011fi Metilasyon De\u011fi\u015fikliklerinin \u0130ncelenmesi\u201d ba\u015fl\u0131kl\u0131 \u00e7al\u0131\u015fma \u00a0\u00a0T\u00dcBITAK taraf\u0131ndan desteklenmeye uygun bulundu. Egeli bilim ekibini makam\u0131nda a\u011f\u0131rlayan Rekt\u00f6r Prof. Dr. Necdet Budak, \u201cTopluma katk\u0131 misyonumuz do\u011frultusunda birey ve toplum sa\u011fl\u0131\u011f\u0131n\u0131 tehdit eden her t\u00fcrl\u00fc sorunun \u00e7\u00f6z\u00fcm\u00fcne y\u00f6nelik \u00f6nemli bilimsel \u00e7al\u0131\u015fmalara ev sahipli\u011fi yapmaya devam ediyoruz. S\u00fcrd\u00fcr\u00fclen bu ara\u015ft\u0131rmalar\u0131n, Ar-Ge ve \u00dcr-Ge faaliyetlerinin projeye, ard\u0131ndan topluma katk\u0131ya d\u00f6n\u00fc\u015febilmesi i\u00e7in bilim insanlar\u0131m\u0131z\u0131, ara\u015ft\u0131rmac\u0131lar\u0131m\u0131z\u0131 her daim motive ederek \u00f6zendirdi\u011fimizi, her t\u00fcrl\u00fc deste\u011fi verdi\u011fimizi bir kez daha vurgulamak isterim. T\u0131p Fak\u00fcltemizden bilim insanlar\u0131, \u00a0glukoz ve fruktozdan olu\u015fan ve mutfaklar\u0131m\u0131zda olduk\u00e7a s\u0131k kulland\u0131\u011f\u0131m\u0131z beyaz rafine \u015fekerin, sadece fruktozdan olu\u015fan do\u011fal meyve \u015fekeri ve sadece glukozdan olu\u015fan malt \u015fekerine g\u00f6re geneti\u011fimizi ve epigeneti\u011fimizi de\u011fi\u015ftirerek h\u00fccrelerimizi ve bizi daha fazla ya\u015fland\u0131rd\u0131\u011f\u0131n\u0131 g\u00f6stermeye \u00e7al\u0131\u015facak. Bu ara\u015ft\u0131rma d\u00fcnyada rafine \u015fekerin genetik ve epigenetik \u00fczerinden ya\u015flanmaya etkilerini ara\u015ft\u0131ran ilk \u00e7al\u0131\u015fma olacak. \u00a0B\u00f6yle \u00f6nemli bir konuyu ara\u015ft\u0131ran bilim ekibimizi tebrik ediyor, ba\u015far\u0131lar\u0131n\u0131n devam\u0131n\u0131 diliyorum\u201d dedi.<\/p>\n
\u201cBilim d\u00fcnyas\u0131na b\u00fcy\u00fck bir katk\u0131 sunulacak\u201d<\/strong><\/p>\n Proje y\u00fcr\u00fct\u00fcc\u00fcs\u00fc Prof. Dr. Haluk Ak\u0131n, \u201c\u00c7evresel etmenlerin, genlerimizden ziyade genlerimizin \u00e7al\u0131\u015fmas\u0131n\u0131 d\u00fczenleyen epigenetik ad\u0131n\u0131 verdi\u011fimiz mekanizmalar\u0131 daha \u00e7ok bozdu\u011funu biliyoruz. Bu \u00e7al\u0131\u015fma ile rafine \u015fekerin epigenetik mekanizmalar \u00fczerinden ya\u015flanmaya etkisini ara\u015ft\u0131raca\u011f\u0131z. Ara\u015ft\u0131rma ekibi, rafine \u015fekerin ya\u015fland\u0131r\u0131c\u0131 etkisini s\u0131\u00e7anlar \u00fczerinde g\u00f6sterecek. 3 ay boyunca bir grup s\u0131\u00e7an, standart s\u0131\u00e7an yeminin yan\u0131nda glukoz ve fruktozdan olu\u015fan beyaz rafine \u015feker ile beslenirken, di\u011fer deney gruplar\u0131ndaki s\u0131\u00e7anlar standart yemin yan\u0131nda sadece glukoz veya sadece fruktoz ile beslenecekler. 3 ay sonunda ara\u015ft\u0131rma ekibi, s\u0131\u00e7anlar\u0131n ya\u015flanmas\u0131n\u0131 hareket ve performans testleri ile de\u011ferlendirdikten sonra karaci\u011ferlerinden ald\u0131klar\u0131 \u00f6rneklerle h\u00fccresel ya\u015flanmay\u0131 histolojik, genetik ve epigenetik seviyede g\u00f6stermeyi ama\u00e7layacak. Sadece fruktozdan olu\u015fan do\u011fal meyve \u015fekeri ya da sadece glukozdan olu\u015fan malt \u015fekerine g\u00f6re do\u011fada \u00e7ok daha nadir bulunan s\u00fckrozdan olu\u015fan fakat g\u00fcn\u00fcm\u00fczde neredeyse her g\u0131dada tatland\u0131r\u0131c\u0131 olarak kulland\u0131\u011f\u0131m\u0131z beyaz \u015fekerin, genetik de\u011fi\u015fikliklere sebep olarak ya\u015flanma s\u00fcrecini h\u0131zland\u0131rd\u0131\u011f\u0131n\u0131 ve h\u00fccrelerimize hasar verdi\u011fini g\u00f6stermeyi ama\u00e7layan proje, d\u00fcnyada rafine \u015fekerin genetik ve epigenetik \u00fczerinden ya\u015flanmaya etkilerini ara\u015ft\u0131ran ilk proje olacak. Ya\u015flanmaya sebep oldu\u011fu bilim \u00e7evreleri taraf\u0131ndan kabul g\u00f6ren h\u00fccresel mekanizmalar ile diyabet ve kalp hastal\u0131klar\u0131 dahil pek \u00e7ok kronik hastal\u0131ktan sorumlu rafine \u015feker t\u00fcketimi aras\u0131nda g\u00fc\u00e7l\u00fc bir ili\u015fki oldu\u011funun ortaya \u00e7\u0131kar\u0131lmas\u0131 durumunda bilim d\u00fcnyas\u0131na b\u00fcy\u00fck bir katk\u0131 sunulacak\u201d dedi.<\/p>\n Multidisipliner bilim ekibi<\/strong><\/p>\n Ara\u015ft\u0131rma ekibi, \u00a0Prof. Dr. Haluk Ak\u0131n, Prof. Dr. L\u00fctfiye Kan\u0131t, Prof. Dr. H\u00fcseyin Aktu\u011f, Do\u00e7. Dr. Ay\u00e7a Aykut, Dr. \u00d6\u011fr. \u00dcyesi Erhan Par\u0131ltay, Ar\u015f. G\u00f6r. Dr. Mert Pekerba\u015f, Ar\u015f. G\u00f6r. Dr. Bilgesu Ak, Ar\u015f. G\u00f6r. Dr. Alper Baysal ve Ar\u015f. G\u00f6r. Dr. Berrin \u00d6zdil\u2019den olu\u015fuyor. Ege \u00dcniversitesi T\u0131p Fak\u00fcltesi T\u0131bbi Genetik Anabilim Dal\u0131, Fizyoloji Anabilim Dal\u0131, Histoloji ve Embriyoloji Anabilim Dal\u0131 ve Ege \u00dcniversitesi Hayvan Deneyleri Merkezi ile ortakla\u015fa ger\u00e7ekle\u015ftirilecek proje 18 ay s\u00fcrecek.<\/p>\n \n \n","protected":false},"excerpt":{"rendered":" Ege \u00dcniversitesi T\u0131p Fak\u00fcltesinde g\u00f6rev yapan bilim insanlar\u0131, g\u0131da end\u00fcstrisinde s\u0131k\u00e7a kullan\u0131lan, halk aras\u0131nda sofra…<\/p>\n","protected":false},"author":2,"featured_media":16120,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69,99,1,11,68],"tags":[],"class_list":["post-16119","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim","category-egitim","category-gncl","category-haber","category-saglik"],"featured_image_urls":{"full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-scaled.jpg",2560,1714,false],"thumbnail":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-150x150.jpg",150,150,true],"medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-300x201.jpg",300,201,true],"medium_large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-768x514.jpg",640,428,true],"large":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-1024x686.jpg",640,429,true],"1536x1536":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-1536x1028.jpg",1536,1028,true],"2048x2048":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-2048x1371.jpg",2048,1371,true],"newsphere-slider-full":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-1280x720.jpg",1280,720,true],"newsphere-featured":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-1024x686.jpg",1024,686,true],"newsphere-medium":["https:\/\/www.euegeajans.com\/wp-content\/uploads\/2023\/08\/EUTF-Tibbi-Genetik-720x380.jpg",720,380,true]},"author_info":{"display_name":"Editor","author_link":"https:\/\/www.euegeajans.com\/index.php\/author\/editor\/"},"category_info":"Bilim<\/a> E\u011fitim<\/a> G\u00fcncel<\/a> Haber<\/a> Sa\u011fl\u0131k<\/a>","tag_info":"Sa\u011fl\u0131k","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/16119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/comments?post=16119"}],"version-history":[{"count":1,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/16119\/revisions"}],"predecessor-version":[{"id":16121,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/posts\/16119\/revisions\/16121"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media\/16120"}],"wp:attachment":[{"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/media?parent=16119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/categories?post=16119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euegeajans.com\/index.php\/wp-json\/wp\/v2\/tags?post=16119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}